ArticleAntimicrobial resistance and infection control2013
The impact of staffing on central venous catheter-associated bloodstream infections in preterm neonates - results of nation-wide cohort study in Germany.
Article in Antimicrobial resistance and infection control, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Antimicrobial-impregnated central venous catheters for preventing neonatal bloodstream infection: the PREVAIL RCT.Health technology assessment (Winchester, England) · 2020Trial
- Increased nurse workload is associated with bloodstream infections in very low birth weight infants.Scientific reports · 2019Trial
- Catheter‑related bloodstream infections and risk factors in infants hospitalized in neonatal intensive care units at Mogadishu, Somalia: two years of experience.BMC pediatrics · 2025Observational
- Multidrug-resistant organisms may be associated with bed allocation and utilization efficiency in healthcare institutions, based on national monitoring data from China (2014-2020).Scientific reports · 2023Article
- Determining the need for additional training among hospital infection-control workforce - results from a multicentric survey within the multiresistance network of southern Lower Saxony (MRNS), Germany.GMS hygiene and infection control · 2022Article
- Chlorhexidine locking device for central line infection prevention in ICU patients: protocol for an open-label pilot and feasibility randomized controlled trial.Pilot and feasibility studies · 2020Article
- Practice variations and rates of late onset sepsis and necrotizing enterocolitis in very preterm born infants, a review.Translational pediatrics · 2019Review
- Overcrowding in a neonatal intermediate care unit: impact on the incidence of multidrug-resistant gram-negative organisms.BMC infectious diseases · 2019Article
- Preventive bundles to reduce catheter-associated bloodstream infections in neonatal intensive care.GMS hygiene and infection control · 2018Article
- Central line-associated bloodstream infections in Australian ICUs: evaluating modifiable and non-modifiable risks in Victorian healthcare facilities.Epidemiology and infection · 2017Article
- Outbreaks in the neonatal ICU: a review of the literature.Current opinion in infectious diseases · 2017Review
- Pathogen-specific mortality in very low birth weight infants with primary bloodstream infection.PloS one · 2017Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVery low birthweight (VLBW) newborns on neonatal intensive care units (NICU) are at increased risk for developing central venous catheter-associated bloodstream infections (CVC BSI). In addition to the established intrinsic risk factors of VLBW newborns, it is still not clear which process and structure parameters within NICUs influence the prevalence of CVC BSI.
methodsThe study population consisted of VLBW newborns from NICUs that participated in the German nosocomial infection surveillance system for preterm infants (NEO-KISS) from January 2008 to June 2009. Structure and process parameters of NICUs were obtained by a questionnaire-based enquiry. Patient based date and the occurrence of BSI derived from the NEO-KISS database. The association between the requested parameters and the occurrance of CVC BSI and laboratory-confirmed BSI was analyzed by generalized estimating equations.
resultsWe analyzed data on 5,586 VLBW infants from 108 NICUs and found 954 BSI cases in 847 infants. Of all BSI cases, 414 (43%) were CVC-associated. The pooled incidence density of CVC BSI was 8.3 per 1,000 CVC days. The pooled CVC utilization ratio was 24.3 CVC-days per 100 patient days. A low realized staffing rate lead to an increased risk of CVC BSI (OR 1.47; p=0.008) and also of laboratory-confirmed CVC BSI (OR 1.78; p=0.028).
conclusionsOur findings show that low levels of realized staffing are associated with increased rates of CVC BSI on NICUs. Further studies are necessary to determine a threshold that should not be undercut.
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