ArticlePloS one2013
The onset of widespread musculoskeletal pain is associated with a decrease in healthy ageing in older people: a population-based prospective study.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- Impact of the Osijek Multidisciplinary Biopsychosocial Program on Chronic Low Back Pain: A Prospective Randomized Controlled Study.International journal of environmental research and public health · 2026Trial
- Bidirectional relationships between pain and alcohol use among older adults: a scoping review.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Adverse childhood experiences and pain incidence and multisite trajectories among middle-aged and older Chinese adults.Pain reports · 2026Article
- Article
- Prevalence and Sociodemographic Correlates of Chronic Pain Among a Nationally Representative Sample of Older Adults in the United States.The journal of pain · 2024Article
- A Pilot Study of a Chronic Pain Self-Management Program Delivered by Community Health Workers to Underserved African American Older Adults.Pain medicine (Malden, Mass.) · 2022Article
- Pain and Its Impact on Functional Health: 7-Year Longitudinal Findings among Middle-Aged and Older Adults in Indonesia.Geriatrics (Basel, Switzerland) · 2020Article
- Article
- Mortality in Relation to Changes in a Healthy Aging Index: The Health, Aging, and Body Composition Study.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019Article
- Older adults' preferences for formal social support of autonomy and dependence in pain: development and validation of a scale.European journal of ageing · 2017Article
- Knee Pain and Structural Damage as Risk Factors for Incident Widespread Pain: Data From the Multicenter Osteoarthritis Study.Arthritis care & research · 2017Article
- Musculoskeletal pain and co-morbid insomnia in adults; a population study of the prevalence and impact on restricted social participation.BMC family practice · 2017Article
- Allostatic load and pain severity in older adults: Results from the English Longitudinal Study of Ageing.Experimental gerontology · 2017Article
- The relationship between perceived promotion of autonomy/dependence and pain-related disability in older adults with chronic pain: the mediating role of self-reported physical functioning.Journal of behavioral medicine · 2016Article
- Successful Aging among Elders Living in the Mani Continental Region vs. Insular Areas of the Mediterranean: the MEDIS Study.Aging and disease · 2016Article
- Musculoskeletal pain in people with and without type 2 diabetes in Taiwan: a population-based, retrospective cohort study.BMC musculoskeletal disorders · 2015Article
- Combined musculoskeletal pain in the upper and lower body: associations with occupational mechanical and psychosocial exposures.International archives of occupational and environmental health · 2015Article
- The Association Between Musculoskeletal Symptoms and Traditional Chinese Medicine Use Among Chinese Older Adults in the Greater Chicago Area.Gerontology & geriatric medicineArticle
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveChronic musculoskeletal pain is common in older adults but the nature of its relationship with ageing is unclear. The objective for this study was to test the hypothesis that the onset of widespread pain would be associated with a decrease in healthy ageing.
methodsPopulation-based prospective cohort study. A "healthy ageing" index was constructed across biomedical, physical, psychosocial and lay components. Analysis was performed with 2949 adults aged 50 years and over who had complete index scores at baseline, 3 and 6-year follow-ups.
resultsAt three and six year follow-up, 365 (16.8%) and 259 (14.3%) experienced the onset of widespread pain. The onset of widespread pain during the six-year period was associated with a 25% and a 46% decrease in healthy ageing index scores; this decrease was independent of age, sex, education, social networks, smoking status, alcohol consumption and physical inactivity. The decrease in healthy ageing attenuated to 20% and 39% following adjustment for diagnosed musculoskeletal conditions and analgesic and non-steroidal use.
conclusionsThe onset of widespread pain was associated with a decrease in healthy ageing throughout the six-year period. When pain increased over time, the markers of unhealthy ageing increased also. Strong analgesia was associated with unhealthy ageing. Research could now usefully test whether early identification, improved treatment and prevention of pain prior to old age may facilitate healthy ageing.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.