ArticleJournal of Parkinson's disease2013
Airway somatosensory deficits and dysphagia in Parkinson's disease.
Article in Journal of Parkinson's disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
What it found
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Who cites it
32 citing papers in PubMed, 69 citations in OpenAlex.
- Assessing Relationships Between Patient and Caregiver Reported Outcome Measures of Dysphagia in Parkinson Disease: A Retrospective Study.Dysphagia · 2026Article
- Characteristics of Swallowing Function in People with Parkinson's Disease: A Scoping Review.Movement disorders : official journal of the Movement Disorder Society · 2026Article
- Is Dysphagia in Multiple System Atrophy Responsive to Levodopa? Results from a Retrospective Study.Movement disorders clinical practice · 2026Article
- Alpha-Synuclein Lesions in the Peripheral Nervous System of the Larynx in Parkinson's Disease.Dysphagia · 2026Article
- Association between Perceived Dysphagia Symptoms and Swallowing Physiology in Parkinson's Disease.Movement disorders clinical practice · 2025Article
- Perspectives on Airway Protection: A Mixed Methods Investigation in People With Parkinson's Disease.American journal of speech-language pathology · 2025Article
- Review
- Cough Correlates of Functional Swallow Outcomes in Atypical Parkinsonism.Movement disorders clinical practice · 2024Article
- A neurocomputational view of the effects of Parkinson's disease on speech production.Frontiers in human neuroscience · 2024Article
- Assessment of the Sensitivity of the Vocal Tract in Parkinson Disease by Nasal Video Endoscopy.International archives of otorhinolaryngology · 2023Article
- [Dysphagia in Parkinsonian Syndromes].Der Nervenarzt · 2023Review
- Dysphagia in Parkinson Disease: Part I - Pathophysiology and Diagnostic Practices.Current physical medicine and rehabilitation reports · 2023Article
- Premotor cortex is hypoactive during sustained vowel production in individuals with Parkinson's disease and hypophonia.Frontiers in human neuroscience · 2023Article
- Gastrointestinal involvement in Parkinson's disease: pathophysiology, diagnosis, and management.NPJ Parkinson's disease · 2022Review
- A multinational consensus on dysphagia in Parkinson's disease: screening, diagnosis and prognostic value.Journal of neurology · 2022Review
- Swallow Safety and Laryngeal Kinematics: A Comparison of Dysphagia Between Parkinson's Disease and Cerebrovascular Accident.Journal of Parkinson's disease · 2022Article
- Respiratory Dysfunctions in Parkinson's Disease Patients.Brain sciences · 2021Review
- Respiratory dysfunction in Parkinson's disease: a narrative review.ERJ open research · 2020Review
- Targeting Chemosensory Ion Channels in Peripheral Swallowing-Related Regions for the Management of Oropharyngeal Dysphagia.International journal of molecular sciences · 2020Review
- Impact of Tussigenic Stimuli on Perceived Upper Airway Sensation and Motor Cough Response Following Total Laryngectomy.Frontiers in physiology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
backgroundIndividuals with Parkinson's disease (PD) often experience substantial impairment of swallow control, and are typically unaware of the presence or severity of their impairments suggesting that these individuals may also experience airway sensory deficits. However, the degree to which impaired swallow function in PD may relate to airway sensory deficits has yet to be formally tested.
objectiveThe purpose of this study was to examine whether airway sensory function is associated with swallow impairment in PD.
methodsEighteen PD participants and 18 healthy controls participated in this study and underwent endoscopic assessment of airway somatosensory function, endoscopic assessment of swallow function, and clinical ratings of swallow and disease severity.
resultsPD participants exhibited abnormal airway somatosensory function and greater swallow impairment compared with healthy controls. Swallow and sensory deficits in PD were correlated with disease severity. Moreover, PD participants reported similar self-rated swallow function as healthy controls, and swallow deficits were correlated with sensory function suggesting an association between impaired sensory function and poor self-awareness of swallow deficits in PD.
conclusionsThese results suggest that control of swallow is influenced by airway somatosensory function, that swallow-related deficits in PD are related to abnormal somatosensation, and that swallow and airway sensory function may degrade as a function of disease severity. Therefore, the basal ganglia and related neural networks may play an important role to integrate airway sensory input for swallow-related motor control. Furthermore, the airway deficits observed in PD suggest a disintegration of swallow-related sensory and motor control.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.