ArticleInternational journal of hepatology2013
Benign hepatocellular tumors in children: focal nodular hyperplasia and hepatocellular adenoma.
Article in International journal of hepatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- A pretreatment multiphasic CT-based decision-support model for differentiating pediatric hepatoblastoma from focal nodular hyperplasia.Frontiers in oncology · 2026Article
- Current approach to diagnosis and treatment of focal nodular hyperplasia in children with a management algorithm.Clinical and experimental hepatology · 2025Review
- Article
- Congenital focal nodular hyperplasia-like lesion mimicking hepatoblastoma: anecdotal but plausible.World journal of pediatric surgery · 2025Article
- Benign paediatric liver tumours: The radiological maze demystified.SA journal of radiology · 2024Article
- Update on the Pathology of Pediatric Liver Tumors: A Pictorial Review.Diagnostics (Basel, Switzerland) · 2023Review
- Preneoplastic liver colonization by 11p15.5 altered mosaic cells in young children with hepatoblastoma.Nature communications · 2023Article
- Utility of the pediatric liver contrast-enhanced ultrasound criteria in differentiating malignant and benign multifocal lesions.Pediatric radiology · 2023Article
- Case Report: Early detection and intervention of congenital portosystemic shunts in children.Frontiers in oncology · 2023Article
- Presentation of Congenital Portosystemic Shunts in Children.Children (Basel, Switzerland) · 2022Review
- Case Report: Rare Acute Abdomen: Focal Nodular Hyperplasia With Spontaneous Rupture.Frontiers in oncology · 2022Article
- Integrated Genomic Analysis Identifies Driver Genes and Cisplatin-Resistant Progenitor Phenotype in Pediatric Liver Cancer.Cancer discovery · 2021Article
- Pediatric Primary Hepatic Tumors: Diagnostic Considerations.Diagnostics (Basel, Switzerland) · 2021Review
- Establishing a Standardized Measure of Quality in Pediatric Liver Surgery: Definition and Validation of Textbook Outcome With Associated Predictors.Frontiers in surgery · 2021Article
- Case Report: Ultrasound-Guided Percutaneous Microwave Ablation of Focal Nodular Hyperplasia in a 9-Year-Old Girl.Frontiers in pediatrics · 2021Article
- Ultrasound-Guided Percutaneous Thermal Ablation of Hepatic Focal Nodular Hyperplasia--A Multicenter Retrospective Study.Frontiers in bioengineering and biotechnology · 2021Article
- Infantile hepatic haemangioendothelioma resection in a newborn: A case report and literature review.The Journal of international medical research · 2020Review
- Hepatocellular adenoma in the paediatric population: Molecular classification and clinical associations.World journal of gastroenterology · 2020Review
- Benign liver tumors in children: outcomes after resection.Pediatric surgery international · 2015Article
- Benign liver tumors in pediatric patients - Review with emphasis on imaging features.World journal of gastroenterology · 2015Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Benign liver tumors are very rare in children. Most focal nodular hyperplasia (FNH) remain sporadic, but predisposing factors exist, as follows: long-term cancer survivor (with an increasing incidence), portal deprivation in congenital or surgical portosystemic shunt. The aspect is atypical on imaging in two-thirds of cases. Biopsy of the tumor and the nontumoral liver is then required. Surgical resection will be discussed in the case of large tumors with or without symptoms. In the case of associated vascular disorder with portal deprivation, restoration of the portal flow will be discussed in the hope of seeing the involution of FNH. HepatoCellular Adenoma (HCA) is frequently associated with predisposing factors such as GSD type I and III, Fanconi anemia especially if androgen therapy is administered, CPSS, and SPSS. Adenomatosis has been reported in germline mutation of HNF1- α . Management will depend on the presence of a predisposing factor and may include metabolic control, androgen therapy withdrawn, or closure of the shunt when appropriate. Surgery is usually performed on large lesions. In the case of adenomatosis or multiple lesions, surgery will be adapted. Close followup is required in all cases.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.