ArticlePloS one2013
Concerted evolution in the ribosomal RNA cistron.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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37 citing papers in PubMed, 83 citations in OpenAlex.
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- Evidence of Biparental Mitochondrial Inheritance from Self-Fertile Crosses between Closely Related Species ofJournal of fungi (Basel, Switzerland) · 2023Article
- Structure-Based GC Investigation Sheds New Light on ITS2 Evolution inInternational journal of molecular sciences · 2023Article
- Beyond Nuclear Ribosomal DNA Sequences: Evolution, Taxonomy, and Closest Known Saprobic Relatives of Powdery Mildew Fungi (Frontiers in microbiology · 2022Article
- Population Diversity and Genetic Structure Reveal Patterns of Host Association and Anthropogenic Impact for the Globally Important Fungal Tree PathogenJournal of fungi (Basel, Switzerland) · 2021Article
- Identification and Characterization of Ceratocystis fimbriata Causing Lethal Wilt on the Lansium Tree in Indonesia.The plant pathology journal · 2021Article
- What Is the Best Lens? Comparing the Resolution Power of Genome-Derived Markers and Standard Barcodes.Microorganisms · 2021Article
- Empirical evidence for concerted evolution in the 18S rDNA region of the planktonic diatom genus Chaetoceros.Scientific reports · 2021Article
- The role of internal transcribed spacer 2 secondary structures in classifying mycoparasitic Ampelomyces.PloS one · 2021Article
- Molecular evidence of the hybrid origin of Cryptocoryne ×purpurea Ridl. nothovar. purpurea (Araceae).PloS one · 2021Article
- The fate of 35S rRNA genes in the allotetraploid grass Brachypodium hybridum.The Plant journal : for cell and molecular biology · 2020Article
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Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGene conversion is the mechanism proposed to be responsible for the homogenization of multigene families such as the nuclear ribosomal gene clusters. This concerted evolutionary process prevents individual genes in gene clusters from accumulating mutations. The mechanism responsible for concerted evolution is not well understood but recombination during meiosis has been hypothesized to play a significant role in this homogenization. In this study we tested the hypothesis of unequal crossing over playing a significant role in gene conversion events within the ribosomal RNA cistron during meiosis, mitosis or both life stages in the fungal tree pathogen Ceratocystis manginecans.
methodsCeratocystis manginecans, a haploid ascomycete, reproduces homothallically and was found to have two distinct sequences within the internally transcribed spacer (ITS) region of the ribosomal RNA cistron. The different ITS types were scored using PCR-RFLP assays and chi-square analyses to determine the level of significance of the changes in the ratios of the ITS types.
resultsThe relative ratios of the two ITS sequence types changed when the fungal isolates were cultured vegetatively or allowed to produced sexual structures and spores. These active changes were shown to occur more frequently during meiosis than mitosis.
conclusionThe evidence presented provides concrete support for homogenization in the rRNA gene clusters found in this fungus and that the most reasonable explanation for this process is unequal crossing over.
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