Evidence map›Paper›PMID 23554243›Full record

ArticleSmall (Weinheim an der Bergstrasse, Germany)2013

Colloid-in-liquid crystal gels that respond to biomolecular interactions.

Ankit Agarwal, Sumyra Sidiq, Shilpa Setia, Emre Bukusoglu, Juan J de Pablo, Santanu Kumar Pal, Nicholas L Abbott

Abstract read
In one paragraph

Article in Small (Weinheim an der Bergstrasse, Germany), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Design of Responsive and Active (Soft) Materials Using Liquid Crystals.Annual review of chemical and biomolecular engineering · 2016
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ankit AgarwalDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, Wisconsin 53706, USA.
Sumyra Sidiq
Shilpa Setia
Emre Bukusoglu
Juan J de Pablo
Santanu Kumar Pal
Nicholas L Abbott

Funding

BIOMOLECULAR ANALYSIS USING LIQUID CRYSTALSR01CA108467 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI ABBOTT, NICHOLAS L · 2004 to 2013
$3.8M
Rapid Analytics for Endotoxin using Liquid Crystalline DropletsR21AI092004 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI ABBOTT, NICHOLAS L · 2011 to 2012
$401k
Nano-Structure Surfaces and Liquid Crystal AnalysisR21CA105730 · NCI · UNIVERSITY OF WISCONSIN MADISON · PI SCHILLER, JOAN H · 2004 to 2005
$259k
NCI NIH HHS CA105730NCI NIH HHS CA108467NCI NIH HHS R01 CA108467NCI NIH HHS R21 CA105730NIAID NIH HHS R21 AI092004
6 · The paper itself

Abstract

This paper advances the design of stimuli-responsive materials based on colloidal particles dispersed in liquid crystals (LCs). Specifically, thin films of colloid-in-liquid crystal (CLC) gels undergo easily visualized ordering transitions in response to reversible and irreversible (enzymatic) biomolecular interactions occurring at the aqueous interfaces of the gels. In particular, LC ordering transitions can propagate across the entire thickness of the gels. However, confinement of the LC to small domains with lateral sizes of ∼10 μm does change the nature of the anchoring transitions, as compared to films of pure LC, due to the effects of confinement on the elastic energy stored in the LC. The effects of confinement are also observed to cause the response of individual domains of the LC within the CLC gel to vary significantly from one to another, indicating that manipulation of LC domain size and shape can provide the basis of a general and facile method to tune the response of these LC-based physical gels to interfacial phenomena. Overall, the results presented in this paper establish that CLC gels offer a promising approach to the preparation of self-supporting, LC-based stimuli-responsive materials.

Indexed as

ColloidsGelsLiquid CrystalsColloidsGelsbiomolecular interfacescolloidsgelsliquid crystalsstimuli-responsive materials

Identifiers

PMID23554243
PMCPMC4025930

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.