ArticleEuropean radiology2013
Quantification and characterisation of coronary artery plaque volume and adverse plaque features by coronary computed tomographic angiography: a direct comparison to intravascular ultrasound.
Article in European radiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
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Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Standards for quantitative assessments by coronary computed tomography angiography (CCTA): An expert consensus document of the society of cardiovascular computed tomography (SCCT).Journal of cardiovascular computed tomographyGuideline
- Atherosclerosis quantification and cardiovascular risk: the ISCHEMIA trial.European heart journal · 2024Trial
- Relationship Between Endothelial Wall Shear Stress and High-Risk Atherosclerotic Plaque Characteristics for Identification of Coronary Lesions That Cause Ischemia: A Direct Comparison With Fractional Flow Reserve.Journal of the American Heart Association · 2016Trial
- Rationale and Design of the CREDENCE Trial: computed TomogRaphic evaluation of atherosclerotic DEtermiNants of myocardial IsChEmia.BMC cardiovascular disorders · 2016Trial
- Computed tomography-based high-risk coronary plaque score to predict acute coronary syndrome among patients with acute chest pain--Results from the ROMICAT II trial.Journal of cardiovascular computed tomographyTrial
- Quantification of plaque and detection of high-risk plaque characteristics based on coronary computed tomography angiography: comparison between superresolution deep learning reconstruction and hybrid iterative reconstruction.Quantitative imaging in medicine and surgery · 2026Article
- Association between serum uric acid and high-risk plaques assessed by coronary CT angiography.Open heart · 2025Article
- Technical principles, benefits, challenges, and applications of photon counting computed tomography in coronary imaging: a narrative review.Cardiovascular diagnosis and therapy · 2024Review
- Coronary computed tomography angiography for clinical practice.Japanese journal of radiology · 2024Review
- Accuracy and limitation of plaque detection by coronary CTA: a section-to-section comparison with optical coherence tomography.Scientific reports · 2023Article
- Non-Contrast and Contrast-Enhanced Cardiac Computed Tomography Imaging in the Diagnostic and Prognostic Evaluation of Coronary Artery Disease.Diagnostics (Basel, Switzerland) · 2023Review
- Diabetes, Atherosclerosis, and Stenosis by AI.Diabetes care · 2023Article
- Relationship of age, atherosclerosis and angiographic stenosis using artificial intelligence.Open heart · 2021Article
- Extraction of Coronary Atherosclerotic Plaques From Computed Tomography Imaging: A Review of Recent Methods.Frontiers in cardiovascular medicine · 2021Review
- A review of serial coronary computed tomography angiography (CTA) to assess plaque progression and therapeutic effect of anti-atherosclerotic drugs.The international journal of cardiovascular imaging · 2020Review
- Improved Evaluation of Lipid-Rich Plaque at Coronary CT Angiography: Head-to-Head Comparison with Intravascular US.Radiology. Cardiothoracic imaging · 2019Article
- Detection of positively remodeled coronary artery lesions by multislice CT and its impact on cardiovascular future events.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2019Article
- Quantification of plaque characteristics detected by dual source computed tomography angiography to predict myocardial ischemia as assessed by single photon emission computed tomography myocardial perfusion imaging.Quantitative imaging in medicine and surgery · 2019Article
- Noninvasive Coronary Plaque Imaging.Journal of atherosclerosis and thrombosis · 2018Review
- Reproducibility of coronary atherosclerotic plaque characteristics in populations with low, intermediate, and high prevalence of coronary artery disease by multidetector computer tomography: a guide to reliable visual coronary plaque assessments.The international journal of cardiovascular imaging · 2016Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe evaluated the performance of manual measures of coronary plaque volumes and atherosclerotic plaque features from coronary CT angiography (CTA), using intravascular ultrasound (IVUS) as the reference.
methodsThirty individual coronary plaques with suitable fiduciary markers were identified. Plaque volumes on coronary CTA were manually quantified by two observers and compared to IVUS plaque volumes as interpreted by an independent laboratory. The presence of adverse plaque characteristics-low attenuation plaque (LAP), positive remodelling (PR) and spotty calcification (SC)-on coronary CTA was evaluated and compared to IVUS.
resultsHigh correlation in plaque volumes was detected between observers (r = 0.94, P < 0.0001; 95 % limits of agreement <48.7 mm(3), bias 6.6 mm(3)). Excellent correlation (r = 0.95, P < 0.0001) was noted in plaque volume between independent observers and IVUS (95 % limits of agreement <40.6 mm(3), bias -4.4 mm(3)) and did not differ from IVUS (105.0 ± 56.7 vs. 109.4 ± 60.7 mm(3), P = 0.2). The frequency of LAP (10 % vs. 17 %), PR (7 % vs. 10 %) and SC (27 % vs. 33 %) was similar between coronary CTA and IVUS (all P = NS).
conclusionsPlaque volume on coronary CTA determined by manual methods demonstrates high correlation and modest agreement to IVUS. Further, coronary CTA demonstrates high accuracy for the identification of adverse plaque characteristics, including LAP, PR and SC. KEY POINTS: • Coronary CT angiography is a non-invasive test that enables coronary plaque assessment • Plaque quantification by coronary CT angiography correlates well with intravascular ultrasound findings • Coronary CT angiography can identify adverse plaque characteristics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.