ArticleCerebellum (London, England)2013
Multidimensional analysis of fetal posterior fossa in health and disease.
Article in Cerebellum (London, England), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Volumetric segmentation in the context of posterior fossa-related pathologies: a systematic review.Neurosurgical review · 2024Pooled it
- MRI radiomics-based approach to predict pituitary neuroendocrine tumor invasiveness.European radiology experimental · 2026Article
- Cerebellar vermis and cerebral fissure evaluation in fetuses with isolated mega cisterna magna: a retrospective magnetic resonance imaging study.BMC medical imaging · 2026Article
- Case Report: A case of Joubert syndrome in twin pregnancy: MRI manifestations and literature review.Frontiers in pediatrics · 2026Article
- The vermian-crest angle: a prediction model for foetal cystic posterior fossa anomalies.Frontiers in neuroscience · 2025Article
- Automatic biometry of fetal brain MRIs using deep and machine learning techniques.Scientific reports · 2023Article
- Fetal neurosurgery.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023Review
- Article
- Normal human brainstem development in vivo: a quantitative fetal MRI study.Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology · 2021Article
- Morphometric development of the human fetal cerebellum during the early second trimester.NeuroImage · 2020Article
- Quantitative approach to the posterior cranial fossa and craniocervical junction in asymptomatic children with achondroplasia.Neuroradiology · 2017Article
- Normative biometry of the fetal brain using magnetic resonance imaging.Brain structure & function · 2017Article
- 3D Super-Resolution Motion-Corrected MRI: Validation of Fetal Posterior Fossa Measurements.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2016Article
- Role of "major" and "minor" lambdoid arch sutures in posterior cranial fossa changes: mechanism of cerebellar tonsillar herniation in infants with multisutural craniosynostosis.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2016Article
- MRI of the Fetal Brain.Clinical neuroradiology · 2015Review
- Costello syndrome: Analysis of the posterior cranial fossa in children with posterior fossa crowding.The neuroradiology journal · 2015Article
- Normal fetal posterior fossa in MR imaging: new biometric data and possible clinical significance.AJNR. American journal of neuroradiology · 2015Article
- Fetal MRI: A Technical Update with Educational Aspirations.Concepts in magnetic resonance. Part A, Bridging education and research · 2014Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
Fetal magnetic resonance imaging (MRI) is now routinely used to further investigate cerebellar malformations detected with ultrasound. However, the lack of 2D and 3D biometrics in the current literature hinders the detailed characterisation and classification of cerebellar anomalies. The main objectives of this fetal neuroimaging study were to provide normal posterior fossa growth trajectories during the second and third trimesters of pregnancy via semi-automatic segmentation of reconstructed fetal brain MR images and to assess common cerebellar malformations in comparison with the reference data. Using a 1.5-T MRI scanner, 143 MR images were obtained from 79 normal control and 53 fetuses with posterior fossa abnormalities that were grouped according to the severity of diagnosis on visual MRI inspections. All quantifications were performed on volumetric datasets, and supplemental outcome information was collected from the surviving infants. Normal growth trajectories of total brain, cerebellar, vermis, pons and fourth ventricle volumes showed significant correlations with 2D measurements and increased in second-order polynomial trends across gestation (Pearson r, p < 0.05). Comparison of normal controls to five abnormal cerebellum subgroups depicted significant alterations in volumes that could not be detected exclusively with 2D analysis (MANCOVA, p < 0.05). There were 15 terminations of pregnancy, 8 neonatal deaths, and a spectrum of genetic and neurodevelopmental outcomes in the assessed 24 children with cerebellar abnormalities. The given posterior fossa biometrics enhance the delineation of normal and abnormal cerebellar phenotypes on fetal MRI and confirm the advantages of utilizing advanced neuroimaging tools in clinical fetal research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.