SynthesisAnnals of oncology : official journal of the European Society for Medical Oncology2013
Cruciferous vegetables consumption and the risk of female lung cancer: a prospective study and a meta-analysis.
Synthesis in Annals of oncology : official journal of the European Society for Medical Oncology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 8 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Broccoli Consumption and Risk of Cancer: An Updated Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2024Pooled it
- Fluoxetine and congenital malformations: a systematic review and meta-analysis of cohort studies.British journal of clinical pharmacology · 2017Pooled it
- Sertraline use in the first trimester and risk of congenital anomalies: a systemic review and meta-analysis of cohort studies.British journal of clinical pharmacology · 2017Pooled it
- A Healthy Dietary Pattern Reduces Lung Cancer Risk: A Systematic Review and Meta-Analysis.Nutrients · 2016Pooled it
- Cigarette smoking during pregnancy and preeclampsia risk: a systematic review and meta-analysis of prospective studies.Oncotarget · 2015Pooled it
- Association of fruit and vegetables with the risk of nasopharyngeal cancer: evidence from a meta-analysis.Scientific reports · 2014Pooled it
- Parity and pancreatic cancer risk: a dose-response meta-analysis of epidemiologic studies.PloS one · 2014Pooled it
- Pooled it
- Dose-dependent detoxication of the airborne pollutant benzene in a randomized trial of broccoli sprout beverage in Qidong, China.The American journal of clinical nutrition · 2019Trial
- Dietary risk factors for lung cancer: an umbrella review of systematic review and meta-analysis.Translational cancer research · 2026Review
- Genotoxicity Studies of Indole-3-carbinol andPharmaceuticals (Basel, Switzerland) · 2026Article
- Chemical Profiling, Analgesic and Anti-Inflammatory Activities ofPlants (Basel, Switzerland) · 2026Article
- Fruit and Vegetable Intake in Relation to Lung Cancer Risk: A Systematic Review and Dose-response Meta-analysis of Prospective Cohort Studies.Journal of cancer prevention · 2025Review
- Development and assessment of an intestinal tri-cellular model to investigate the pro/anti-inflammatory potential of digested foods.Frontiers in immunology · 2025Article
- Formation of DNA Adducts by 1-Methoxy-3-indolylmethylalcohol, a Breakdown Product of a Glucosinolate, in the Mouse: Impact of the SULT1A1 Status-Wild-Type, Knockout or Humanised.International journal of molecular sciences · 2024Article
- Antioxidant and Antiproliferative Activities of Kale (Molecules (Basel, Switzerland) · 2023Article
- Therapeutic Potential of Plant Oxylipins.International journal of molecular sciences · 2022Review
- Phytochemicals in Gynecological Cancer Prevention.International journal of molecular sciences · 2021Review
- Pre-diagnosis Cruciferous Vegetables and Isothiocyanates Intake and Ovarian Cancer Survival: A Prospective Cohort Study.Frontiers in nutrition · 2021Article
- Functional Ingredients FromInternational journal of molecular sciences · 2020Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
backgroundEpidemiological studies evaluating the association between cruciferous vegetables (CVs) intake and female lung cancer risk have produced inconsistent results. PATIENTS AND
methodsThis study followed 74 914 Chinese women aged 40-70 years who participated in the Shanghai Women's Health Study. CV intake was assessed through a validated food-frequency questionnaire (FFQ) at baseline and reassessed during follow-up. Hazard ratios (HRs) and 95% confidence interval (CIs) were estimated by using Cox proportional hazards models. Furthermore, we carried out a meta-analysis of all observational studies until December 2011.
resultsAfter excluding the first 2 years of follow-up, 417 women developed lung cancer over a mean of 11.1 years of follow-up. An inverse association of borderline statistical significance was observed between CV consumption and female lung cancer risk, with HR for the highest compared with the lowest quartiles of 0.73 (95% CI 0.54-1.00, P trend = 0.1607). The association was strengthened in analyses restricting to never smokers, with the corresponding HR of 0.59 (95% CI 0.40-0.87, P trend = 0.0510). The finding of an inverse association between CV intake and lung cancer risk in women was supported by our meta-analysis of 10 included studies.
conclusionsOur study suggests that CV consumption may reduce the risk of lung cancer in women, particularly among never smokers.
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