Evidence map›Paper›PMID 23552821›Full record

Trial reportJournal of addiction medicine

Eight weeks of exercise training improves fitness measures in methamphetamine-dependent individuals in residential treatment.

Brett A Dolezal, Joy Chudzynski, Thomas W Storer, Marlon Abrazado, Jose Penate, Larissa Mooney, Daniel Dickerson, Richard A Rawson, Christopher B Cooper

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 6 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 6 syntheses or guidelines pooled it, 90 citations in OpenAlex.

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  6. Methamphetamine-Related Disorders.Deutsches Arzteblatt international · 2017
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Brett A DolezalExercise Physiology Research Laboratory, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA. bdolezal@mednet.ucla.edu
Joy Chudzynski
Thomas W Storer
Marlon Abrazado
Jose Penate
Larissa Mooney
Daniel Dickerson
Richard A Rawson
Christopher B Cooper
University of California, Los Angeles · US

Funding

Aerobic Exercise to Improve Outcomes of Treatment for Methamphetamine DependenceR01DA027633 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI RAWSON, RICHARD A · 2009 to 2014
$2.7M
NIDA NIH HHS R01 DA027633
6 · The paper itself

Abstract

objectivesPhysical exercise has been shown to benefit diverse medical and behavioral conditions. This study assesses the feasibility and efficacy of an 8-week endurance and resistance training program on fitness measures in individuals undergoing residential treatment for methamphetamine (MA) dependence.

methodsA total of 39 MA-dependent individuals were randomized to 3 days/week of exercise training (ET, n = 15) or health education without training (equal attention [EA], n = 14) over 8 weeks. Aerobic performance ((Equation is included in full-text article.)VO2max) was measured by indirect calorimetry, body composition by skinfolds, muscle strength by 1-repetition maximum (1-RM), and endurance at 85% of 1-RM for both leg press (LP) and chest press (CP).

resultsA total of 29 individuals completed the study for a 74% adherence rate. Baseline characteristics (mean ± SD) were balanced between groups: age 31 ± 7 years; height = 1.74 ± 0.07 m; weight 82.0 ± 15.0 kg. The ET group significantly improved (Equation is included in full-text article.)O2max by 0.63 ± 0.22 L/min (+21%), LP strength by 24.4 ± 5.6 kg (+40%), and CP strength by 20.6 ± 5.7 kg (+49%). The ET group increased LP and CP endurance by 120% and 96%, respectively and showed significant reductions in body weight of 1.7 ± 2.4 kg (-2%), % body fat of 2.8 ± 1.3% (-15%), and fat weight 2.8 ± 1.8 kg (-18%). All changes were significant (P < 0.001) for ET, and no changes were seen for the EA group.

conclusionsIndividuals recovering from MA dependence showed substantial improvements in aerobic exercise performance, muscle strength and endurance, and body composition with ET. These findings demonstrate the feasibility of an ET intervention in these participants and also show excellent responsiveness to the exercise stimulus resulting in physiological changes that might enhance recovery from drug dependency.

Indexed as

MethamphetamineAdolescentAdultAmphetamine-Related DisordersBody CompositionCalorimetry, IndirectCentral Nervous System StimulantsExerciseFeasibility StudiesFemaleHealth BehaviorHealth EducationHumansMaleMiddle AgedMuscle StrengthCentral Nervous System StimulantsMethamphetamine

Identifiers

PMID23552821
PMCPMC3617407
OpenAlexW1980856462

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.