Evidence map›Paper›PMID 23551928›Full record

Trial reportThe journal of sexual medicine2013

Psychological correlates of sexual dysfunction in female rectal and anal cancer survivors: analysis of baseline intervention data.

Errol J Philip, Christian Nelson, Larissa Temple, Jeanne Carter, Leslie Schover, Sabrina Jennings, Lina Jandorf, Tatiana Starr, Ray Baser, Katherine DuHamel

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The journal of sexual medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pelvic floor rehabilitation in cancer survivorship: an umbrella review.Journal of cancer survivorship : research and practice · 2026
    Pooled it
  2. Non-gastrointestinal symptom burden following colorectal cancer treatment-a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  3. Guideline
  4. Trial
  5. Trial
  6. Review
  7. Review
  8. Article
  9. Sexual function and disease progression in women with advanced cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  10. Patient interest in the Lowdown on Down There: attendance at a vulvovaginal and sexual health workshop post-cancer treatment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
    Article
  11. Review
  12. Sexual quality of life, body image distress, and psychosocial outcomes in colorectal cancer: a longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2018
    Article
  13. Article
  14. Facilitating psychosexual adjustment for women undergoing pelvic radiotherapy: pilot of a novel patient psycho-educational resource.Health expectations : an international journal of public participation in health care and health policy · 2016
    Article
  15. Article
  16. Investigation of body image as a mediator of the effects of bowel and GI symptoms on psychological distress in female survivors of rectal and anal cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2016
    Article
  17. Article
  18. Baseline characteristics and concerns of female cancer patients/survivors seeking treatment at a Female Sexual Medicine Program.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2015
    Article
  19. Pelvic radiotherapy and sexual function in women.Translational andrology and urology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Errol J PhilipDepartment of Psychiatry & Behavioral Sciences, Memorial Sloan-Kettering Cancer Center, New York, NY, USA.
Christian Nelson
Larissa Temple
Jeanne Carter
Leslie Schover
Sabrina Jennings
Lina Jandorf
Tatiana Starr
Ray Baser
Katherine DuHamel
Memorial Sloan Kettering Cancer Center · USIcahn School of Medicine at Mount Sinai · USThe University of Texas MD Anderson Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Psychosocial Palliative & Community Research in CancerT32CA009461 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI JENNIFER L HAY, Jamie S. Ostroff · 1985 to 2026
$10.1M
The Sexual Rehabilitation of Rectal Cancer Survivors: A Pilot StudyR21CA129195 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI DUHAMEL, KATHERINE N · 2007 to 2008
$412k
NCI NIH HHS P30 CA008748NCI NIH HHS R21 CA129195NCI NIH HHS R21 CA129195-01NCI NIH HHS T32 CA009461NCI NIH HHS T32CA009461-28
6 · The paper itself

Abstract

introductionSexual dysfunction represents a complex and multifactorial construct that can affect both men and women and has been noted to often deteriorate significantly after treatment for rectal and anal cancer. Despite this, it remains an understudied, underreported, and undertreated issue in the field of cancer survivorship.

aimThis study examined the characteristics of women enrolled in an intervention trial to treat sexual dysfunction, and explored the relationship between sexual functioning and psychological well-being.

methodsThere were 70 female posttreatment anal or rectal cancer survivors assessed as part of the current study. Participants were enrolled in a randomized intervention trial to treat sexual dysfunction and completed outcome measures prior to randomization. MAIN OUTCOMES MEASURES: The main outcome measures are quality of life (QOL) (European Organization for Research and Treatment of Cancer Core Quality of Life Questionnaire [EORTC-QLQ-C30] and Colorectal Cancer-Specific Module [QLQ-CR38]), sexual functioning (Female Sexual Functioning Index), and psychological well-being (Brief Symptom Inventory Depression/Anxiety, Impact of Events Scale-Revised, CR-38 Body Image).

resultsWomen enrolled in the study intervention were on average 55 years old, predominantly Caucasian (79%), married (57%), and a median of 4 years postprimary treatment. For those reporting sexual activity at baseline (N=41), sexual dysfunction was associated with a range of specific measures of psychological well-being, all in the hypothesized direction. The Sexual/Relationship Satisfaction subscale was associated with all measures of psychological well-being (r=-0.45 to -0.70, all P<0.01). Body image, anxiety, and cancer-specific posttraumatic distress were notable in their association with subscales of sexual functioning, while a global QOL measure was largely unrelated.

conclusionsFor sexually active female rectal and anal cancer survivors enrolled in a sexual health intervention, sexual dysfunction was significantly and consistently associated with specific measures of psychological well-being, most notably Sexual/Relationship Satisfaction. These results suggest that sexual functioning may require focused assessment by providers, beyond broad QOL assessments, and that attention to Sexual/Relationship Satisfaction may be critical in the development and implementation of interventions for this cohort of patients.

Indexed as

Quality of LifeSexual BehaviorAdultAgedAged, 80 and overAnus NeoplasmsAnxietyBody ImageDepressionFemaleHumansMaleMarital StatusMiddle AgedNew York CityPersonal SatisfactionPsychological DistressRectal CancerSexual DysfunctionSexual Health

Identifiers

PMID23551928
PMCPMC3706574
OpenAlexW1517404123

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.