Trial reportVeterinary surgery : VS2013
Effects of negative pressure wound therapy on healing of free full-thickness skin grafts in dogs.
Trial report in Veterinary surgery : VS, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 72 citations in OpenAlex.
- A preliminary study of the effect of closed incision management with negative pressure wound therapy over high-risk incisions.BMC veterinary research · 2015Trial
- Negative pressure wound therapy: experience in 45 dogs.Veterinary surgery : VS · 2014Trial
- Two-stage reconstruction using basic fibroblast growth factor-impregnated artificial dermis and acellular fish skin graft in a dog with distal extremity soft tissue sarcoma.The Journal of veterinary medical science · 2026Article
- Autologous, free omentum grafts for large, open, distal limb wounds in dogs: Technique and outcome in 10 dogs.Veterinary surgery : VS · 2026Article
- Application of negative pressure wound therapy to partially closed median sternotomy in a dog.The Canadian veterinary journal = La revue veterinaire canadienne · 2025Article
- Nigeria bee honey-enhanced adherence, neovascularisation and epithelisation of full-thickness skin autografts on distal extremities of dogs.BMC veterinary research · 2022Article
- Filling the vacuum: Role of negative pressure wound therapy in open wound management in cats.Journal of feline medicine and surgery · 2021Review
- Evaluation of angiogenesis, inflammation, and healing on irradiated skin graft with low-level laser therapy in rats (Rattus norvegicus albinus wistar).Lasers in medical science · 2020Article
- Effects of red and near-infrared LED light therapy on full-thickness skin graft in rats.Lasers in medical science · 2020Article
- Feasibility of a disposable canister-free negative-pressure wound therapy (NPWT) device for treating open wounds in horses.BMC veterinary research · 2019Article
- Retrospective comparison of negative pressure wound therapy and silver-coated foam dressings in open-wound treatment in cats.Journal of feline medicine and surgery · 2017Article
- Changes in histopathology and cytokeratin AE1/AE3 expression in skin graft with different time on Indonesian local cats.Veterinary world · 2017Article
- Subjective and objective observation of skin graft recovery on Indonesian local cat with different periods of transplantation time.Veterinary world · 2016Article
- Negative pressure wound therapy augmented full-thickness free skin grafting in the cat: outcome in 10 grafts transferred to six cats.Journal of feline medicine and surgery · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo compare healing of free, full-thickness, meshed skin grafts under negative pressure wound therapy (NPWT) with bolster dressings in dogs. STUDY
designRandomized, controlled experimental study, paired design. ANIMALS: Dogs (n = 5)
methodsFull-thickness skin wounds (4 cm × 1.5 cm) were created bilaterally on the antebrachia of 5 dogs (n = 10). Excised skin was grafted to the contralateral limb. Grafts were randomized to NPWT or bolster dressings (control; CON). NPWT was applied continuously for 7 days. Grafts were evaluated on Days 2, 4, 7, 10, 14, and 17, biopsied on days 0, 4, 7, and 14, and had microbial culture on Day 7. Outcome variables were: time to first appearance of granulation tissue, percent graft necrosis, and percent open mesh. Significance was set at P < .05. Histologic findings, culture results, and graft appearance were reported.
resultsGranulation tissue appeared earlier in the NPWT grafts compared with CON grafts. Percent graft necrosis and remaining open mesh area were both greater in CON grafts compared with NPWT grafts at most time points. Histologic results showed no significant difference in all variables measured, and all cultures were negative.
conclusionsVariables of graft acceptance were superior when NPWT was used in the first week post-grafting. Fibroplasia was enhanced, open meshes closed more rapidly and less graft necrosis occurred with NPWT application. More preclinical studies are required to evaluate histologic differences.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.