Evidence map›Paper›PMID 23550135›Full record

ArticleG3 (Bethesda, Md.)2013

Population structure in a comprehensive genomic data set on human microsatellite variation.

Trevor J Pemberton, Michael DeGiorgio, Noah A Rosenberg

Open access · goldAbstract read
In one paragraph

Article in G3 (Bethesda, Md.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 171 citations in OpenAlex.

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  6. Mathematical constraints onPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
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  9. On the heterozygosity of an admixed population.Journal of mathematical biology · 2020
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  13. Testing the utility of dental morphological trait combinations for inferring human neutral genetic variation.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  14. Diversity and Conflict.Econometrica : journal of the Econometric Society · 2020
    Article
  15. Article
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  19. Article
  20. Assessing the relative impact of historical divergence and inter-group transmission on cultural patterns: a method from evolutionary ecology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Trevor J PembertonDepartment of Biology, Stanford University, Stanford, California 94305, USA. pembertont@med.umanitoba.ca
Michael DeGiorgio
Noah A Rosenberg
Stanford University · USUniversity of California, Berkeley · US

Funding

Population genetics for large-scale sequencing studies of diverse populationsR01HG005855 · NHGRI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Noah Rosenberg, Paul A Scheet · 2010 to 2026
$5.8M
Population-Genetic Studies for Association MappingR01GM081441 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI ROSENBERG, NOAH · 2007 to 2011
$1.7M
NHGRI NIH HHS HG005855NHGRI NIH HHS R01 HG005855NIGMS NIH HHS GM081441NIGMS NIH HHS R01 GM081441
6 · The paper itself

Abstract

Over the past two decades, microsatellite genotypes have provided the data for landmark studies of human population-genetic variation. However, the various microsatellite data sets have been prepared with different procedures and sets of markers, so that it has been difficult to synthesize available data for a comprehensive analysis. Here, we combine eight human population-genetic data sets at the 645 microsatellite loci they share in common, accounting for procedural differences in the production of the different data sets, to assemble a single data set containing 5795 individuals from 267 worldwide populations. We perform a systematic analysis of genetic relatedness, detecting 240 intra-population and 92 inter-population pairs of previously unidentified close relatives and proposing standardized subsets of unrelated individuals for use in future studies. We then augment the human data with a data set of 84 chimpanzees at the 246 loci they share in common with the human samples. Multidimensional scaling and neighbor-joining analyses of these data sets offer new insights into the structure of human populations and enable a comparison of genetic variation patterns in chimpanzees with those in humans. Our combined data sets are the largest of their kind reported to date and provide a resource for use in human population-genetic studies.

Indexed as

Databases, GeneticGenetics, PopulationGenetic VariationGenomicsAllelesAnimalsGenetic LociGenome, HumanGeographyHeterozygoteHumansMicrosatellite RepeatsPan troglodytesPhylogenyPopulation DynamicsReproducibility of Resultspopulation structurerelativesshort tandem repeats

Identifiers

PMID23550135
PMCPMC3656735
OpenAlexW2114325165

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.