Evidence map›Paper›PMID 23549680›Full record

Trial reportLasers in medical science2014

Clinical evaluation of the efficiency of low-level laser therapy for oral lichen planus: a prospective case series.

Adriana Cafaro, Paolo Giacomo Arduino, Gianluca Massolini, Ercole Romagnoli, Roberto Broccoletti

Registry-linked trialOpen access · greenAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Lasers in medical science, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05951361 (Evaluation of Diode Laser and Topical Steroid Therapy in the Treatment of Erosive Oral Lichen Planus), which is not on this map. Cited by 24 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 5 pooled it
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05951361 nacompletednot on this mapstarted 2022, after this paper: background citation

Evaluation of Diode Laser and Topical Steroid Therapy in the Treatment of Erosive Oral Lichen Planus (A Randomized Controlled Clinical Trial)

TypeinterventionalSponsorAlexandria UniversityRan2022 to 2023Enrolled44ConditionsErosive Oral Lichen PlanusArms980nm Diode Laser, 0.1% topical triamcinolone Acetonide preparation "Kenacourt-A Orabase"
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 73 citations in OpenAlex.

  1. Pooled it
  2. Efficacy of Topical Treatments for the Management of Symptomatic Oral Lichen Planus: A Systematic Review.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adriana CafaroOral Medicine Section, Department of Surgical Sciences, University of Turin, UNITO LINGOTTO DENTAL INSTITUTE c/o Lingotto, Via Nizza 230, 10126, Turin, Italy.
Paolo Giacomo Arduino
Gianluca Massolini
Ercole Romagnoli
Roberto Broccoletti
University of Turin · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral lichen planus (OLP) is an inflammatory disease that can be painful, mainly in the atrophic and erosive forms. Numerous drugs have been used with dissimilar results, but most treatments are empirical. However, to date, the most commonly employed and useful agents for the treatment of OLP are topical corticosteroids. The study objective was to detail the clinical effectiveness of low-level laser therapy (LLLT) for the management of OLP unresponsive to standard topical therapy. The authors studied a prospective cohort of 30 patients affected by OLP, who received biostimulation with a 980-nm gallium-aluminum-arsenide (GaAIAs) diode laser (DM980, distributed by DMT S.r.l., Via Nobel 33, 20035, Lissone, Italy). Outcome variables, statistically evaluated, were: the size of lesions; visual analogue score of pain and stability of the therapeutic results in the follow-up period. Eighty-two lesions were treated. We reported significant reduction in clinical scores of the treated lesions and in reported pain. No detailed complications or therapy side effects were observed during the study. As previously reported by our group with a preliminary report, this study suggests that LLLT could be a possible treatment choice for patients with unresponsive symptomatic OLP, also reducing the possible invasiveness correlated with other therapies.

Indexed as

Low-Level Light TherapyAgedCohort StudiesFemaleHumansLasers, SemiconductorLichen Planus, OralMaleMiddle AgedPainProspective StudiesTreatment Outcome

Identifiers

PMID23549680
OpenAlexW2077767224

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.