ArticleInternational journal of ophthalmology2013
Green-light fundus autofluorescence in diabetic macular edema.
Article in International journal of ophthalmology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Monotherapy laser photocoagulation for diabetic macular oedema.The Cochrane database of systematic reviews · 2018Pooled it
- Fundus Autofluorescence in Diabetic Retinopathy.Journal of personalized medicine · 2024Review
- Quantitative Color Fundus Autofluorescence in Patients with Diabetes Mellitus.Journal of clinical medicine · 2020Article
- Granular lesions of short-wavelength and near-infrared autofluorescence in diabetic macular oedema.Eye (London, England) · 2019Article
- Clinical relevance of quantified fundus autofluorescence in diabetic macular oedema.Eye (London, England) · 2015Article
- Scanning laser 'en face' retinal imaging of epiretinal membranes.Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society · 2014Article
- Assessment of β-zone peripapillary atrophy by optical coherence tomography and scanning laser ophthalmoscopy imaging in glaucoma patients.Clinical ophthalmology (Auckland, N.Z.) · 2014Article
- Correlation between peripapillary retinal nerve fiber layer thickness and fundus autofluorescence in primary open-angle glaucoma.Clinical ophthalmology (Auckland, N.Z.) · 2013Article
- Autofluorescence indexes as biomarkers for antiangiogenic loading dose outcome in diabetic macular edema.Therapeutic advances in ophthalmologyArticle
- Fundus Autofluorescence and Clinical Applications.Journal of ophthalmic & vision researchReview
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo evaluate the role of central green-light fundus autofluorescence (FAF) in diabetic macular edema (DME).
methodsA consecutive series of 92 study eyes with diabetic retinopathy were included. Out of those, 51 diabetic eyes had DME and were compared to 41 diabetic eyes without DME. In all subjects, green-light FAF images were obtained, quantified and classified into various FAF patterns. Cross-sectional optical coherence tomography (OCT) scans were obtained for evaluation of Inner/Outer segment (IS/OS) layer integrity, measurements of central RPE-IS/OS layer thickness as well as classification of DME into various subtypes.
resultsMean central green-light FAF intensity of eyes with DME (1.289±0.140)log did not significantly differ from diabetic patients without DME (1.317±0.137)log. Most classifiable FAF patterns were seen in patients with cystoid DME. Mean central retinal thickness (CRT) of all study eyes with DME was (501.9±112.4)µm compared to (328.2±27.0)µm in diabetic patients without DME. Patients with DME had significantly more disrupted photoreceptor IS/OS layers than diabetic patients without DME (28/51 vs 5/41, P<0.001). Mean RPE-IS/OS thickness of patients with DME (60.7±14.1)µm was significantly (P<0.001) lower than in diabetic eyes without DME (73.5±9.4)µm. Correlation analys1s revealed non-significant correlations of green-light FAF intensity and OCT parameters in all subtypes of DME.
conclusionOur results indicate a poor correlation of central green-light FAF intensity with CRT, IS/OS layer integrity or RPE-IS/OS layer thickness in diabetic patients with or without DME and its various subtypes. Thus, central green-light FAF is not suitable for detection of retinal thickening in DME.
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