ArticleClinical rheumatology2013
Risk factors for body composition abnormalities in systemic sclerosis.
Article in Clinical rheumatology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 56 citations in OpenAlex.
- A meta-analysis of fracture risk and bone mineral density in patients with systemic sclerosis.Clinical rheumatology · 2020Pooled it
- Trial
- Validity of Bioelectrical Impedance Analysis for the Assessment of Body Composition in Patients With Systemic Sclerosis.Journal of cachexia, sarcopenia and muscle · 2026Article
- Article
- Assessment of Factors Related to Sarcopenia in Patients with Systemic Sclerosis.Journal of clinical medicine · 2025Article
- High-Protein Nutritional Supplements Improve Nutritional Status in Malnourished Patients with Systemic Sclerosis.Nutrients · 2024Article
- Nutritional disorders and nutrition-related conditions: an underestimated clinical problem in systemic sclerosis.Reumatologia · 2024Review
- In the Pursuit of Metabolic Markers of Systemic Sclerosis-Plasma Adiponectin and Omentin-1 in Monitoring the Course of the Disease.International journal of molecular sciences · 2023Article
- Prevalence and clinical association of sarcopenia among Thai patients with systemic sclerosis.Scientific reports · 2022Article
- The Involvement of Smooth Muscle, Striated Muscle, and the Myocardium in Scleroderma: A Review.International journal of molecular sciences · 2022Review
- The need to accurately measure energy intake and expenditure in patients with systemic sclerosis.Journal of scleroderma and related disorders · 2022Article
- Symptoms related to gastrointestinal tract involvement and low muscularity in systemic sclerosis.Clinical rheumatology · 2022Article
- Sarcopenia in rheumatic disorders: what the radiologist and rheumatologist should know.Skeletal radiology · 2022Review
- Prevalence and predictive factors of osteoporosis in Thai systemic sclerosis.Scientific reports · 2021Article
- HDL cholesterol efflux capacity and lipid profile in patients with systemic sclerosis.Arthritis research & therapy · 2021Article
- Body composition and bone status in relation to microvascular damage in systemic sclerosis patients.Journal of endocrinological investigation · 2021Article
- Reduction of fat free mass index and phase angle is a risk factor for development digital ulcers in systemic sclerosis patients.Clinical rheumatology · 2020Article
- Sarcopenia in Autoimmune and Rheumatic Diseases: A Comprehensive Review.International journal of molecular sciences · 2020Review
- Sarcopenia in systemic sclerosis: the impact of nutritional, clinical, and laboratory features.Rheumatology international · 2019Article
- Malnutrition and sarcopenia in a large cohort of patients with systemic sclerosis.Clinical rheumatology · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to evaluate the body composition (BC), bone mineral density (BMD), and the food intake in women with systemic sclerosis (SSc) compared to a control group, in order to identify main risk factors for BC abnormalities in SSc. Sixty-one SSc women and 67 age- and gender-matched controls were included. Spine, femur, and total body BMD measurements were performed using dual-energy X-ray absorptiometry. BC measurements included total lean (LM), fat mass (FM), and relative skeletal muscle mass index (RSMI) assessment. The food intake was calculated from 3-day food records and transformed into energy and nutrients. The 61 SSc patients [30 with diffuse cutaneous disease (dcSSc) and 31 with limited cutaneous SSc (lcSSc)] had significantly lower body mass index (BMI), LM, and FM, as well as lower BMD values compared to controls. Besides, the group with dcSSc, but not those with lcSSc, showed significantly lower BC and BMD measurements than controls. There was a significant inverse correlation between disease duration and BMI, LM, and RSMI. The total energy, macronutrients, and essential amino acids intakes were similar between patients and controls. After multivariate analysis, longer disease duration was the only risk factor associated with sarcopenia (RSMI below 5.45 kg/m(2); OR = 1.36, 95% CI 1.07-1.7). The present study showed an abnormal BC and a lower BMD, especially in dcSSc women, regardless of current food intake. Longer disease duration was associated with a higher risk of sarcopenia in SSc patients.
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Registered trials
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