ReviewInternational journal of molecular sciences2013
Plant nucleotide binding site-leucine-rich repeat (NBS-LRR) genes: active guardians in host defense responses.
Review in International journal of molecular sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 166 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
166 citing papers in PubMed, 2 syntheses or guidelines pooled it, 374 citations in OpenAlex.
- Role of the Genetic Background in Resistance to Plant Viruses.International journal of molecular sciences · 2018Pooled it
- Genetic basis of qualitative and quantitative resistance to powdery mildew in wheat: from consensus regions to candidate genes.BMC genomics · 2013Pooled it
- Genome-wide cyclin gene evolution in Arabidopsis and Brassica reveals polyploidization-driven duplication and flowering-time associations.Molecular genetics and genomics : MGG · 2026Article
- Identification of race-specific QTL and candidate genes for Aphanomyces root rot resistance in alfalfa (Medicago sativa L.).G3 (Bethesda, Md.) · 2026Article
- Genome-wide association mapping and characterization of genetic loci associated with resistance against wheat streak mosaic virus.BMC plant biology · 2026Article
- A One Health Framework for Proteomics Across the Tree of Life to Advance Food Security, Animal Health, and Ecosystem Resilience.Proteomes · 2026Review
- Identification of the NBS-LRR gene family and AkNBS-LRR43 and 100 functional analysis under biotic stress.Plant cell reports · 2026Article
- Genome-wide identification and expression analysis of the NBS-LRR gene family in Citrus clementina.Scientific reports · 2026Article
- Identification and Development of Pathogen- and Pest-Specific Defense-Resistance-Associated SSR Marker Candidates Assisted by Machine Learning and Discovery of Putative QTL Hotspots inPlants (Basel, Switzerland) · 2026Article
- Enhanced Soybean Immunity to the Soybean Mosaic Virus Through RNA Interference Targeting thePlants (Basel, Switzerland) · 2026Article
- Novel PCR markers for discriminatingFrontiers in plant science · 2026Article
- Overexpression of a novel CC-NBS-LRR gene NtRPP13 confers enhanced resistance to Ralstonia solanacearum in tobacco.Plant cell reports · 2025Article
- Fine mapping of the Co-Bf gene conferring broad-spectrum resistance to the anthracnose pathogen of common bean (Phaseolus vulgaris L.).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Reactive oxygen species production and signal transduction in response to stress triggered by Alternaria elicitors in Brassicaceae.Plant molecular biology · 2025Review
- High Basal Expression and Dual Stress Responsiveness of Soybean (Plants (Basel, Switzerland) · 2025Article
- Noncoding elements in wheat defence response to fusarium head blight.Scientific reports · 2025Article
- INCREASED DNA METHYLATION 3 forms a potential chromatin remodelling complex with HAIRPLUS to regulate DNA methylation and trichome development in tomato.The Plant journal : for cell and molecular biology · 2025Article
- Super pangenome of Vitis empowers identification of downy mildew resistance genes for grapevine improvement.Nature genetics · 2025Article
- Phylogenetic, Structural, and Evolutionary Insights into Pepper NBS-LRR Resistance Genes.International journal of molecular sciences · 2025Article
- Unraveling key genes and pathways involved in Verticillium wilt resistance by integrative GWAS and transcriptomic approaches in Upland cotton.Functional & integrative genomics · 2025Article
106 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most represented group of resistance genes are those of the nucleotide binding site-leucine-rich repeat (NBS-LRR) class. These genes are very numerous in the plant genome, and they often occur in clusters at specific loci following gene duplication and amplification events. To date, hundreds of resistance genes and relatively few quantitative trait loci for plant resistance to pathogens have been mapped in different species, with some also cloned. When these NBS-LRR genes have been physically or genetically mapped, many cases have shown co-localization between resistance loci and NBS-LRR genes. This has allowed the identification of candidate genes for resistance, and the development of molecular markers linked to R genes. This review is focused on recent genomics studies that have described the abundance, distribution and evolution of NBS-LRR genes in plant genomes. Furthermore, in terms of their expression, NBS-LRR genes are under fine regulation by cis- and trans-acting elements. Recent findings have provided insights into the roles of alternative splicing, the ubiquitin/ proteasome system, and miRNAs and secondary siRNAs in the regulation of NBS-LRR gene expression at the post-transcriptional, post-translational and epigenetic levels. The possibility to use this knowledge for genetic improvement of plant resistance to pathogens is discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.