ArticleEuropean journal of clinical nutrition2013
Fatty-acid composition of maternal and umbilical cord plasma and early childhood atopic eczema in a Spanish cohort.
Article in European journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 51 citations in OpenAlex.
- Maternal Factors Associated with Levels of Fatty Acids, Specifically n-3 PUFA during Pregnancy: ECLIPSES Study.Nutrients · 2021Trial
- Assessment of DHA on reducing early preterm birth: the ADORE randomized controlled trial protocol.BMC pregnancy and childbirth · 2017Trial
- Omega-3 cord plasma proportions and cognitive function trajectories from 5 to 15 years of age: a population-based cohort study.European journal of epidemiology · 2026Article
- Maternal Nutrition During Pregnancy and Fetal Outcome, Short- and Long-Term Health Effects: A Narrative Review.Nutrients · 2026Review
- Global Comparison of Erythrocyte EPA and DHA Concentrations in Pregnant Women.The Journal of nutrition · 2026Article
- Specialized Pro-Resolving Lipid Mediators and Dietary Omega-3/6 Fatty Acids in Selected Inflammatory Skin Diseases: A Systematic Review.Antioxidants (Basel, Switzerland) · 2025Review
- Maternal prenatal nut and seafood consumption and child neuropsychological function from 4 to 15 years of age: a population-based cohort study.The American journal of clinical nutrition · 2025Article
- Fatty acid signatures in people with HIV: association with adverse pregnancy outcomes and offspring anthropometrics.Journal of acquired immune deficiency syndromes (1999) · 2025Article
- The Causal Relationship Between Circulating Metabolites and the Risk of Atopic Dermatitis: A Two-Sample Mendelian Randomization Study.Clinical, cosmetic and investigational dermatology · 2025Article
- Association of Fatty Acid Signatures with HIV Viremia in Pregnancy.AIDS research and human retroviruses · 2024Observational
- Prenatal polyunsaturated fatty acids and atopic dermatitis and food allergy in children from Polish Mother and Child Cohort study.International journal of occupational medicine and environmental health · 2023Article
- Nutritional Modulation of Associations between Prenatal Exposure to Persistent Organic Pollutants and Childhood Obesity: A Prospective Cohort Study.Environmental health perspectives · 2023Article
- Causal effects of fatty acids on atopic dermatitis: A Mendelian randomization study.Frontiers in nutrition · 2023Article
- Novel Interactions of Myristic Acid andNutrients · 2022Article
- Long-Chain Polyunsaturated Fatty Acid Status at Birth and Development of Childhood Allergy: A Systematic Review.Life (Basel, Switzerland) · 2022Review
- Changes in fatty acid levels (saturated, monounsaturated and polyunsaturated) during pregnancy.BMC pregnancy and childbirth · 2021Article
- Article
- Proportions of Polyunsaturated Fatty Acids in Umbilical Cord Blood at Birth Are Related to Atopic Eczema Development in the First Year of Life.Nutrients · 2021Article
- Maternal Nutritional Status and Development of Atopic Dermatitis in Their Offspring.Clinical reviews in allergy & immunology · 2021Review
- Maternal Supply of Both Arachidonic and Docosahexaenoic Acids Is Required for Optimal Neurodevelopment.Nutrients · 2021Review
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
objectivesFatty-acid status during in-utero development might influence the risk of atopic diseases in early childhood. The aim of this work was to identify the relationship between maternal plasma and cord blood fatty acid (FA) composition and the risk of atopic eczema in the offspring at 14 months of age. SUBJECTS/
methodsTwo hundred and eleven non-atopic mothers and their children were studied. Mothers were recruited in their first trimester of gestation and children were monitored until 14 months of age. Samples of maternal plasma and cord blood plasma were analyzed to determine the FA profile of total lipids. Presence of atopic eczema in the infants was documented through questionnaires at 6 and 14 months of age.
resultsHigher concentrations of total long-chain polyunsaturated FA (LC-PUFA) were found in maternal plasma of non-atopic children in relation to atopic group. Moreover, this maternal plasma LC-PUFA content was negatively correlated with the atopic eczema (odds ratios (OR)=0.83, P=0.04) in infants. Regarding cord blood samples, docosahexaenoic acid (DHA C22:6n3) and the sum of total n-3 and of LC-PUFA n-3 showed a negative correlation with the prevalence of the disease (OR=0.50, 0.49 and 0.49, respectively).
conclusionsOur results show that the fatty-acid status of the fetus during pregnancy has an important role in the development of atopic eczema in early childhood. The prevalence of this atopic disorder is related to lower cord blood plasma levels of FA belonging to n-3 series, especially DHA.
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