ArticleClinical pharmacology and therapeutics2013
A cell simulator platform: the cell collective.
Article in Clinical pharmacology and therapeutics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- VIOLIN: A modular framework for scalable reconciliation of heterogeneous interaction graphs.bioRxiv : the preprint server for biology · 2026Article
- AI-driven virtual cell models in preclinical research: technical pathways, validation mechanisms, and clinical translation potential.NPJ digital medicine · 2025Review
- Normalizing Input-Output Relationships of Cancer Networks for Reversion Therapy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- A large-scale Boolean model of the rheumatoid arthritis fibroblast-like synoviocytes predicts drug synergies in the arthritic joint.NPJ systems biology and applications · 2023Article
- Metabolomics meets systems immunology.EMBO reports · 2023Review
- The nonlinearity of regulation in biological networks.NPJ systems biology and applications · 2023Article
- A multiscale mechanistic model of human dendritic cells forFrontiers in immunology · 2023Article
- A practical guide to mechanistic systems modeling in biology using a logic-based approach.Briefings in bioinformatics · 2021Review
- RunBioSimulations: an extensible web application that simulates a wide range of computational modeling frameworks, algorithms, and formats.Nucleic acids research · 2021Article
- Setting the basis of best practices and standards for curation and annotation of logical models in biology-highlights of the [BC]2 2019 CoLoMoTo/SysMod Workshop.Briefings in bioinformatics · 2021Review
- HIV and Proteomics: What We Have Learned from High Throughput Studies.Proteomics. Clinical applications · 2021Review
- Emerging whole-cell modeling principles and methods.Current opinion in biotechnology · 2018Review
- Identification of Biologically Essential Nodes via Determinative Power in Logical Models of Cellular Processes.Frontiers in physiology · 2018Article
- A Mechanistic Computational Model Reveals That Plasticity of CD4Frontiers in physiology · 2018Article
- A systems pharmacology model for inflammatory bowel disease.PloS one · 2018Article
- Logical Reduction of Biological Networks to Their Most Determinative Components.Bulletin of mathematical biology · 2016Article
- Systems Perturbation Analysis of a Large-Scale Signal Transduction Model Reveals Potentially Influential Candidates for Cancer Therapeutics.Frontiers in bioengineering and biotechnology · 2016Article
- Logical Modeling and Dynamical Analysis of Cellular Networks.Frontiers in genetics · 2016Review
- Integrating interactive computational modeling in biology curricula.PLoS computational biology · 2015Article
- Sensitivity analysis of biological Boolean networks using information fusion based on nonadditive set functions.BMC systems biology · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Diseases are often a result of multiple malfunctions in complex, nonlinear biological/biochemical networks. As such, these processes are far more complicated to understand because they tend to give rise to functions that are emergent in nature, i.e., higher-level (mal)functions that are more than the sum of their parts. Systems biology provides a new approach to understanding biological systems and diseases from a holistic perspective.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.