ArticleJournal of clinical and experimental neuropsychology2013
The aggregate effects of multiple comorbid risk factors on cognition among HIV-infected individuals.
Article in Journal of clinical and experimental neuropsychology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- HIV, Vascular Risk Factors, and Cognition in the Combination Antiretroviral Therapy Era: A Systematic Review and Meta-Analysis.Journal of the International Neuropsychological Society : JINS · 2021Pooled it
- Is There Any Evidence of Premature, Accentuated and Accelerated Aging Effects on Neurocognition in People Living with HIV? A Systematic Review.AIDS and behavior · 2021Pooled it
- Review
- The Effects of Prescribed Medications on Depressive Symptoms and Neurocognitive Performance in People With HIV.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025Article
- The relationship between synaptodendritic neuropathology and HIV-associated neurocognitive disorders is moderated by cognitive reserve.Journal of neurovirology · 2023Article
- Racial differences in health and cognition as a function of HIV among older adults.The Clinical neuropsychologist · 2022Article
- Reduced Working Memory is Associated with Heavier Alcohol Consumption History, Role Impairment and Executive Function Difficulties.AIDS and behavior · 2021Article
- Lifetime antiretroviral exposure and neurocognitive impairment in HIV.Journal of neurovirology · 2020Article
- Use of Neuroimaging to Inform Optimal Neurocognitive Criteria for Detecting HIV-Associated Brain Abnormalities.Journal of the International Neuropsychological Society : JINS · 2020Article
- Clinical and neuroimaging correlates of cognition in HIV.Journal of neurovirology · 2019Article
- Effects of comorbidity burden and age on brain integrity in HIV.AIDS (London, England) · 2019Observational
- A Novel Role of Prolidase in Cocaine-Mediated Breach in the Barrier of Brain Microvascular Endothelial Cells.Scientific reports · 2019Article
- Empiric neurocognitive performance profile discovery and interpretation in HIV infection.Journal of neurovirology · 2019Article
- Cannabis Consumption in People Living with HIV: Reasons for Use, Secondary Effects, and Opportunities for Health Education.Cannabis and cannabinoid research · 2019Article
- Lifetime marijuana and alcohol use, and cognitive dysfunction in people with human immunodeficiency virus infection.Substance abuse · 2018Article
- Redefining Aging in HIV Infection Using Phenotypes.Current HIV/AIDS reports · 2017Review
- Cognitive reserve and neuropsychological functioning in older HIV-infected people.Journal of neurovirology · 2016Article
- Cocaine Enhances HIV-1 Transcription in Macrophages by Inducing p38 MAPK Phosphorylation.Frontiers in microbiology · 2016Article
- Impact of cocaine abuse on HIV pathogenesis.Frontiers in microbiology · 2015Review
- HIV-associated neurocognitive disorders: the relationship of HIV infection with physical and social comorbidities.BioMed research international · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
This study developed and then cross-validated a novel weighting algorithm based on multiple comorbid risk factors (stimulant use, vascular disease, hepatitis C, HIV disease severity, cognitive reserve) to predict cognitive functioning among 366 HIV+ adults. The resultant "risk severity score" was used to differentially weight, as a function of age, the impact and magnitude of multiple risk factors on cognition. Among older adults (≥50 years) the risk severity index was differentially predictive of learning/memory and verbal fluency, whereas among younger adults it was linked to working memory and executive function. Cognitive reserve was found to be the most robust predictor of neurocognition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.