Evidence map›Paper›PMID 23546812›Full record

ArticleJIMD reports2013

Motor and speech disorders in classic galactosemia.

Nancy L Potter, Yves Nievergelt, Lawrence D Shriberg

Registry-linked trialOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JIMD reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03838016 (Babble Boot Camp), which is not on this map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
33.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03838016 early_phase1completednot on this mapstarted 2019, after this paper: background citation

Babble Boot Camp: Preventing Speech and Language Disorders in Children With Classic Galactosemia

TypeinterventionalSponsorArizona State UniversityRan2019 to 2025Enrolled285ConditionsClassic Galactosemia, Speech Disorders in Children, Language Disorders in ChildrenArmsBabble Boot Camp
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

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  19. Tongue Strength in Children With and Without Speech Sound Disorders.American journal of speech-language pathology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Nancy L PotterDepartment of Speech and Hearing Sciences, Washington State University Spokane, 412 E. Spokane Falls Blvd., Spokane, WA, 99202-2131, USA, nlpotter@wsu.edu.
Yves Nievergelt
Lawrence D Shriberg
Eastern Washington University · USUniversity of Wisconsin–Madison · USWashington State University Spokane · US

Funding

WISCONSIN CENTER ON MENTAL RETARDATION: CORE SUPPORTP30HD003352 · NICHD · UNIVERSITY OF WISCONSIN-MADISON · PI MESSING, ALBEE · 1985 to 2015
$25.2M
STUDIES IN DEVELOPMENTAL PHONOLOGICAL DISORDERSR01DC000496 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI SHRIBERG, LAWRENCE D · 1988 to 2017
$9.9M
NICHD NIH HHS P30 HD003352NIDCD NIH HHS R01 DC000496
6 · The paper itself

Abstract

Purpose To test the hypothesis that children with classic galactosemia and speech disorders are at risk for co-occurring strength and coordination disorders. Method This is a case-control study of 32 children (66% male) with galactosemia and neurologic speech disorders and 130 controls (50% male) ages 4-16 years. Speech was assessed using the Percentage of Consonants Correct (PCC) metric from responses to the Goldman-Fristoe Test of Articulation-2 and from a 5-min recorded speech sample, hand and tongue strength using the Iowa Oral Performance Instrument, and coordination using the Movement Assessment Battery for Children. The number of days on milk during the neonatal period was obtained by parent report. Analyses of covariance, distributions, and correlations were used to evaluate relationships among speech, strength, coordination, age, gender, and days on milk. Results Children with galactosemia had weaker hand and tongue strength and most (66%) had significant coordination disorders, primarily affecting balance and manual dexterity. Among children with galactosemia, children with more speech errors and classified as childhood apraxia of speech (n = 7) and ataxic dysarthria (n = 1), had poorer balance and manual dexterity, but not weaker hand or tongue strength, compared to the children with fewer speech errors. The number of days on milk during the neonatal period was associated with more speech errors in males but not in females. Conclusion Children with galactosemia have a high prevalence of co-occurring speech, coordination, and strength disorders, which may be evidence of a common underlying etiology, likely associated with diffuse cerebellar damage, rather than distinct disorders.

Identifiers

PMID23546812
PMCPMC3755563
OpenAlexW1807430561

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.