GuidelineNature reviews. Cardiology2013
Position statement of the World Heart Federation on the prevention and control of rheumatic heart disease.
Guideline in Nature reviews. Cardiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 140 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
140 citing papers in PubMed, 11 syntheses or guidelines pooled it, 293 citations in OpenAlex.
- Severe adverse reactions to benzathine penicillin G in rheumatic heart disease: A systematic review and meta-analysis.PloS one · 2025Pooled it
- Global prevalence and sex differences in rheumatic heart disease: a systematic review and updated meta-analysis.Frontiers in cardiovascular medicine · 2025Pooled it
- Pooled it
- Pooled it
- Current Situation of Acute Rheumatic Fever and Rheumatic Heart Disease in Latin America and the Caribbean: A Systematic Review.Global heart · 2022Pooled it
- Prevalence of rheumatic heart disease among school children in East Africa: a systematic review and meta-analysis.The Pan African medical journal · 2021Pooled it
- Integrating the Prevention and Control of Rheumatic Heart Disease into Country Health Systems: A Systematic Review and Meta-Analysis.Global heart · 2020Pooled it
- Prevalence and progression of rheumatic heart disease: a global systematic review and meta-analysis of population-based echocardiographic studies.Scientific reports · 2019Pooled it
- The role of social determinants of health in the risk and prevention of group A streptococcal infection, acute rheumatic fever and rheumatic heart disease: A systematic review.PLoS neglected tropical diseases · 2018Pooled it
- Correlation of angiotensin I-converting enzyme gene insertion/deletion polymorphism with rheumatic heart disease: a meta-analysis.Bioscience reports · 2016Pooled it
- Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communiqué.Cardiovascular journal of AfricaGuideline
- The global burden of rheumatic heart disease: 1990-2021.Clinical medicine (London, England) · 2026Article
- Elevated Interleukin-6 Levels in Socioeconomically Disadvantaged Children With Borderline Subclinical Rheumatic Heart Disease in São Paulo, Brazil: A Prospective Cohort Study Highlighting Early Detection and Treatment Opportunities.Journal of the American Heart Association · 2026Article
- Article
- Rheumatic Heart Disease in Europe: Insights from a Pilot Screening Study and a Scoping Review.Global heart · 2026Article
- The "Cairo Accord"- towards the eradication of RHD: revisited (2026).Frontiers in cardiovascular medicine · 2026Review
- Stakeholders Want a Menu of Choices: Findings from a Consultation Workshop on Improving Access to Secondary Prophylaxis of Rheumatic Fever and Rheumatic Heart Disease.Global heart · 2026Article
- Article
- Characteristics and Problems of Rheumatic Heart Disease in Indonesia: The Ina-RHD Multicenter Study.JACC. Asia · 2025Article
- The burden of rheumatic heart disease and issues affecting the provision of care in Malawi: A scoping review.PLoS neglected tropical diseases · 2025Article
80 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the 21(st) century, rheumatic fever (RF) and rheumatic heart disease (RHD) are neglected diseases of marginalized communities. Globally, RHD remains the most-common cardiovascular disease in young people aged <25 years. Although RF and RHD have been almost eradicated in areas with established economies, migration from low-income to high-income settings might be responsible for a new burden of RHD in high-income countries. The World Heart Federation (WHF) and its Working Group on RF and RHD unites global experts, combines their experience and enthusiasm, and provides a platform for RHD control. This paper is a declaration of the WHF institutional strategic goal--a 25% reduction in premature deaths from RF and RHD among individuals aged <25 years by the year 2025. The position statement affirms WHF commitments to five key strategic targets: comprehensive register-based control programmes, global access to benzathine penicillin G, identification and development of public figures as 'RHD champions', expansion of RHD training hubs, and support for vaccine development. In this paper, we also review existing barriers to RF and RHD control and identify the actions required to change the trajectory of control for these diseases. This approach provides the foundation for governments, civil society, patient advocates, clinicians, researchers, and funding agencies to develop partnerships and unify global efforts to control RF and RHD. The WHF plans to expand this position statement to an operational plan that will be founded on science, research, and quantifiable progress indicators to impact positively on the millions of people who are affected by RHD and its long-term sequelae.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.