Evidence map›Paper›PMID 23546018›Full record

ReviewChromosoma2013

Condensin: crafting the chromosome landscape.

Ilaria Piazza, Christian H Haering, Anna Rutkowska

Abstract readReview
PubMed Publisher
In one paragraph

Review in Chromosoma, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Molecular characteristics of early-stage female germ cells revealed by RNA sequencing of low-input cells and analysis of genome-wide DNA methylation.DNA research : an international journal for rapid publication of reports on genes and genomes · 2019
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Nesprin-2 Interacts with Condensin Component SMC2.International journal of cell biology · 2017
    Article
  9. Article
  10. Review
  11. Genome maintenance in the context of 4D chromatin condensation.Cellular and molecular life sciences : CMLS · 2016
    Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ilaria PiazzaCell Biology and Biophysics Unit, Structural and Computational Biology Unit, European Molecular Biology Laboratory, EMBL, Meyerhofstr. 1, 69117 Heidelberg, Germany.
Christian H Haering
Anna Rutkowska
European Molecular Biology Laboratory · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The successful transmission of complete genomes from mother to daughter cells during cell divisions requires the structural re-organization of chromosomes into individualized and compact structures that can be segregated by mitotic spindle microtubules. Multi-subunit protein complexes named condensins play a central part in this chromosome condensation process, but the mechanisms behind their actions are still poorly understood. An increasing body of evidence suggests that, in addition to their role in shaping mitotic chromosomes, condensin complexes have also important functions in directing the three-dimensional arrangement of chromatin fibers within the interphase nucleus. To fulfill their different functions in genome organization, the activity of condensin complexes and their localization on chromosomes need to be strictly controlled. In this review article, we outline the regulation of condensin function by phosphorylation and other posttranslational modifications at different stages of the cell cycle. We furthermore discuss how these regulatory mechanisms are used to control condensin binding to specific chromosome domains and present a comprehensive overview of condensin's interaction partners in these processes.

Indexed as

Adenosine TriphosphatasesAnimalsCell DivisionChromosomesDNA-Binding ProteinsHumansMultiprotein ComplexesPhosphorylationProtein BindingAdenosine Triphosphatasescondensin complexesDNA-Binding ProteinsMultiprotein Complexes

Identifiers

PMID23546018
OpenAlexW1966294446

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.