Evidence map›Paper›PMID 23545368›Full record

ReviewSeminars in cell & developmental biology2013

Inner ear supporting cells: rethinking the silent majority.

Guoqiang Wan, Gabriel Corfas, Jennifer S Stone

Open access · greenAbstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 92 papers.

0numbers the graph read from it
0cells of the map it votes in
92citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

92 citing papers in PubMed, 164 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Cochlear isolation in neonatal mice forFrontiers in pharmacology · 2026
    Article
  5. Article
  6. Hair cell loss - cause or consequence of hearing loss?Frontiers in cell and developmental biology · 2026
    Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Localization of cadherins in the postnatal cochlear epithelium and their relation to space formation.Developmental dynamics : an official publication of the American Association of Anatomists · 2024
    Article
  18. Article
  19. Review
  20. bioRxiv : the preprint server for biology · 2024
    Article

32 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Guoqiang WanFM Kirby Neurobiology Center, Children's Hospital Boston, MA 02115, USA.
Gabriel Corfas
Jennifer S Stone
Boston Children's Hospital · USUniversity of Washington · US

Funding

SYNAPTIC MECHANISMS IN HIPPOCAMPAL EPILEPTOGENESISP30HD018655 · NICHD · CHILDREN'S HOSPITAL BOSTON · PI POMEROY, SCOTT LOREN · 1985 to 2015
$26.2M
Trophic Interactions in the Developing and Adult Inner EarR01DC004820 · NIDCD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CORFAS, GABRIEL · 2002 to 2019
$6.2M
NICHD NIH HHS P30 HD018655NIDCD NIH HHS R01 DC004820
6 · The paper itself

Abstract

Sensory epithelia of the inner ear contain two major cell types: hair cells and supporting cells. It has been clear for a long time that hair cells play critical roles in mechanoreception and synaptic transmission. In contrast, until recently the more abundant supporting cells were viewed as serving primarily structural and homeostatic functions. In this review, we discuss the growing information about the roles that supporting cells play in the development, function and maintenance of the inner ear, their activities in pathological states, their potential for hair cell regeneration, and the mechanisms underlying these processes.

Indexed as

AnimalsCell PolarityCell TransdifferentiationGene Expression Regulation, DevelopmentalHair Cells, AuditoryHumansLabyrinth Supporting CellsMechanotransduction, CellularMorphogenesisMutationRegenerationSensory Receptor CellsSynapsesSynaptic TransmissionTranscription FactorsTranscription Factors

Identifiers

PMID23545368
PMCPMC4005836
OpenAlexW1979510752

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.