ArticleFrontiers in neuroscience2013
Serotonin and the regulation of mammalian energy balance.
Article in Frontiers in neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
74 citing papers in PubMed, 1 synthesis or guideline pooled it, 146 citations in OpenAlex.
- Long-Term Effects of Intrauterine Exposure to Antidepressants on Physical, Neurodevelopmental, and Psychiatric Outcomes: A Systematic Review.The Journal of clinical psychiatry · 2020Pooled it
- Wheat Protein Hydrolysate Fortified With l-Arginine Enhances Satiation Induced by the Capsaicinoid Nonivamide in Moderately Overweight Male Subjects.Molecular nutrition & food research · 2019Trial
- Characterization and postprandial regulation of the nutrient-sensing machinery in the oral floor mucosa of 10-week-old mule ducks.Poultry science · 2026Article
- Serotonin Signaling and Vascular Reactivity in Cardiometabolic Disease and Cardiac Surgery.Cells · 2026Review
- Impact of Kefir on the Gut-Brain Axis: Serotonin Metabolism and Signaling in Pediatric Rats.Microorganisms · 2025Article
- Unraveling the Connections: Eating Issues, Microbiome, and Gastrointestinal Symptoms in Autism Spectrum Disorder.Nutrients · 2025Review
- Serotoninergic modulation in the brainstem and hypothalamus of female overnourished rats: impact on mitochondrial markers, oxidative stress and BDNF mRNA levels.Frontiers in molecular biosciences · 2025Article
- Spontaneous running wheel exercise during pregnancy prevents later neonatal-anoxia-induced somatic and neurodevelopmental alterations.IBRO neuroscience reports · 2024Article
- The association between the fluoxetine use and the occurrence of coronary heart disease: a nationwide retrospective cohort study.BMC cardiovascular disorders · 2024Article
- Serotonin receptor-mediated vasorelaxation occurs primarily through 5-HTPhysiological reports · 2024Article
- Interactions between Lateral Hypothalamic Orexin and Dorsal Raphe Circuitry in Energy Balance.Brain sciences · 2024Article
- Novel lncRNA regulatory elements in milk somatic cells of Holstein dairy cows associated with mastitis.Communications biology · 2024Article
- The microbiota-gut-brain axis and neurodevelopmental disorders.Protein & cell · 2023Review
- Altered 5-HT2A/C receptor binding in the medulla oblongata in the sudden infant death syndrome (SIDS): Part I. Tissue-based evidence for serotonin receptor signaling abnormalities in cardiorespiratory- and arousal-related circuits.Journal of neuropathology and experimental neurology · 2023Article
- Impacts of Different Prenatal Supplementation Strategies on the Plasma Metabolome of Bulls in the Rearing and Finishing Phase.Metabolites · 2023Article
- Duration of ergovaline exposure influences serotonin-mediated vasoactivity of bovine mesenteric vasculature.Journal of animal science · 2023Article
- Maternal methyl donor supplementation regulates the effects of cafeteria diet on behavioral changes and nutritional status in male offspring.Food & nutrition research · 2023Article
- Microbiota-gut-brain axis and ketogenic diet: how close are we to tackling epilepsy?Microbiome research reports · 2023Review
- Unraveling the periprandial changes in brain serotonergic activity and its correlation with food intake-related neuropeptides in rainbow troutFrontiers in endocrinology · 2023Article
- Systematic investigation of imprinted gene expression and enrichment in the mouse brain explored at single-cell resolution.BMC genomics · 2022Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Maintenance of energy balance requires regulation of the amount and timing of food intake. Decades of experiments utilizing pharmacological and later genetic manipulations have demonstrated the importance of serotonin signaling in this regulation. Much progress has been made in recent years in understanding how central nervous system (CNS) serotonin systems acting through a diverse array of serotonin receptors impact feeding behavior and metabolism. Particular attention has been paid to mechanisms through which serotonin impacts energy balance pathways within the hypothalamus. How upstream factors relevant to energy balance regulate the release of hypothalamic serotonin is less clear, but work addressing this issue is underway. Generally, investigation into the central serotonergic regulation of energy balance has had a predominantly "hypothalamocentric" focus, yet non-hypothalamic structures that have been implicated in energy balance regulation also receive serotonergic innervation and express multiple subtypes of serotonin receptors. Moreover, there is a growing appreciation of the diverse mechanisms through which peripheral serotonin impacts energy balance regulation. Clearly, the serotonergic regulation of energy balance is a field characterized by both rapid advances and by an extensive and diverse set of central and peripheral mechanisms yet to be delineated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.