Evidence map›Paper›PMID 23543830›Full record

ArticleACS medicinal chemistry letters2012

Structure Activity Relationship Study of the Cleistriosides and Cleistetrosides for Antibacterial/Anticancer Activity.

Pei Shi, Michelle C Silva, Hua-Yu Leo Wang, Bulan Wu, Novruz G Akhmedov, Miaosheng Li, Penny J Beuning, George A O'Doherty

Abstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Chemical communications (Cambridge, England) · 2022
    Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Chemical science · 2014
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Pei ShiDepartment of Chemistry and Chemical Biology, Northeastern University, Boston, MA 02115.
Michelle C Silva
Hua-Yu Leo Wang
Bulan Wu
Novruz G Akhmedov
Miaosheng Li
Penny J Beuning
George A O'Doherty

Funding

De Novo Synthesis of OligosaccharidesR01GM090259 · NIGMS · WEST VIRGINIA UNIVERSITY · PI O'DOHERTY, GEORGE A · 2009 to 2012
$1.2M
NIGMS NIH HHS R01 GM090259
6 · The paper itself

Abstract

Two known cleistriosides and six known cleistetrosides were synthesized and evaluated for anticancer and antibacterial activity. This study, for the first time, reports anticancer activity and comprehensively the antibacterial activity for these oligosaccharide natural products. In addition, two new unnatural cleistetroside analogues were synthesized and tested. Biological activities for the ten oligosaccharides against

Indexed as

antibacterialanticancerCleistetrosideCleistriosidePalladium-catalyzed glycosylation

Identifiers

PMID23543830
PMCPMC3610185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.