ArticleJournal of autism and developmental disorders2013
Sensitivity and specificity of proposed DSM-5 criteria for autism spectrum disorder in toddlers.
Article in Journal of autism and developmental disorders, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Health Knowledge About Early Diagnosis of Autism Spectrum Disorders: A Case for Soft Transdiagnostic Approaches to Better Represent the Clinical and Scientific Reality of ASD.International journal of environmental research and public health · 2025Pooled it
- How has DSM-5 Affected Autism Diagnosis? A 5-Year Follow-Up Systematic Literature Review and Meta-analysis.Journal of autism and developmental disorders · 2020Pooled it
- The Effects of DSM-5 Criteria on Number of Individuals Diagnosed with Autism Spectrum Disorder: A Systematic Review.Journal of autism and developmental disorders · 2015Pooled it
- How will DSM-5 affect autism diagnosis? A systematic literature review and meta-analysis.Journal of autism and developmental disorders · 2014Pooled it
- DSM-5 based algorithms for the Autism Diagnostic Interview-Revised for children ages 4-17 years.Journal of child psychology and psychiatry, and allied disciplines · 2025Article
- Male and Female Toddlers with DSM-5 Autism Spectrum Disorder have Similar Developmental Profiles and Core Autism Symptoms.Journal of autism and developmental disorders · 2024Article
- Review
- Symptoms of autism spectrum disorder and developmental delay in children with low mental age.The Clinical neuropsychologist · 2022Article
- Autism Diagnostic Interview-Revised Within DSM-5 Framework: Test of Reliability and Validity in Chinese Children.Journal of autism and developmental disorders · 2022Article
- Identifying Subgroups of Toddlers with DSM-5 Autism Spectrum Disorder Based on Core Symptoms.Journal of autism and developmental disorders · 2021Article
- The Toddler Autism Symptom Inventory: Use in diagnostic evaluations of toddlers.Autism : the international journal of research and practice · 2021Article
- DSM-5 symptom expression in toddlers.Autism : the international journal of research and practice · 2021Article
- Diagnosing Autism Spectrum Disorder in Toddlers Born Very Preterm: Estimated Prevalence and Usefulness of Screeners and the Autism Diagnostic Observation Schedule (ADOS).Journal of autism and developmental disorders · 2021Article
- How well are DSM-5 diagnostic criteria for ASD represented in standardized diagnostic instruments?European child & adolescent psychiatry · 2021Article
- Video-Based Training in Recognizing Exemplars of Autism Spectrum Disorder Diagnostic Criteria.Training and education in professional psychology · 2020Article
- A comparative study of the genetic components of three subcategories of autism spectrum disorder.Molecular psychiatry · 2019Article
- Development and validation of DSM-5 based diagnostic tool for children with Autism Spectrum Disorder.PloS one · 2019Article
- Comparison of DSM-IV-TR and DSM-5 Criteria in Diagnosing Autism Spectrum Disorders in Singapore.Journal of autism and developmental disorders · 2018Article
- Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood.Journal of autism and developmental disorders · 2017Article
- Diagnostic Utility of the ADI-R and DSM-5 in the Assessment of Latino Children and Adolescents.Journal of autism and developmental disorders · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Autism spectrum disorder (ASD) diagnosis is based on behavioral presentation; changes in conceptual models or defining behaviors may significantly impact diagnosis and uptake of ASD-specific interventions. The literature examining impact of DSM-5 criteria is equivocal. Toddlers may be especially vulnerable to the stringent requirements of impairment in all three social-communication symptoms and two restricted/repetitive symptoms. Receiver operating characteristic (ROC) curves identified optimal cutoffs for sums of ADOS and ADI-R criteria mapped to each criterion for 422 toddlers. The optimal modification of DSM-5 criteria (sensitivity = 0.93, specificity = 0.74) required meeting the ROC-determined cutoffs for 2/3 Domain A criteria and 1 point for 1/4 Domain B criteria. This modification will help insure that ASD is identified accurately in young children, facilitating ASD-specific early intervention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.