ArticleJournal of clinical and diagnostic research : JCDR2013
The HLA Class II Associations with Rheumatic Heart Disease in South Indian Patients: A Preliminary Study.
Article in Journal of clinical and diagnostic research : JCDR, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed, 7 citations in OpenAlex.
- A case of rheumatic valvular heart disease and autoimmune gastritis.BMJ case reports · 2014Article
- Rheumatic heart disease in Uganda: the association between MHC class II HLA DR alleles and disease: a case control study.BMC cardiovascular disorders · 2014Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
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Abstract
introductionRheumatic heart disease (RHD) occurs in 30-45% of the patients with rheumatic fever (RF) and it leads to chronic valvular lesions. The human leukocyte antigen (HLA) might confer a susceptibility to RHD. The aim of the present study was to determine the prevalent HLA class II DR/DQ allelic types which were associated with rheumatic heart disease (RHD) in a small group of south Indian patients and to compare them with those in the control subjects.
methodsA total of 23 patients who were diagnosed with RHD and 6 control samples were included in this study. A low resolution HLA Class II DR/DQ typing was performed on the blood samples by the PCR-SSP method. RESULTS AND
conclusionThe DRB3*01:01:02:01 allele showed a positive association with RHD, whereas the DQB1 loci alleles did not show any significant association.
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