ReviewClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2013
Muscle cramps in liver disease.
Review in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Placebo Controlled Study of Baclofen in the Treatment of Muscle Cramps in Patients With Cirrhosis
Effect of Branched-chain Amino Acids (BCAA) to Muscle Cramps in Patients With Cirrhosis
Who cites it
16 citing papers in PubMed, 51 citations in OpenAlex.
- Efficacy and Safety of Pregabalin for Muscle Cramps in Liver Cirrhosis: A Double-Blind Randomized Controlled Trial.Journal of Korean medical science · 2022Trial
- Impact of L-carnitine on imatinib-related muscle cramps in patients with gastrointestinal stromal tumor.Investigational new drugs · 2020Trial
- Muscle Cramps Do Not Improve With Correction of Vitamin D Insufficiency.WMJ : official publication of the State Medical Society of Wisconsin · 2017Trial
- Multidimensional transcriptome dataset for systematic evaluation of Jakyakgamcho-tang-induced cell signatures.Scientific data · 2026Article
- Effect of L-carnitine supplementation on muscle cramps in liver cirrhosis: results from a retrospective cohort study.BMC gastroenterology · 2025Article
- Commonly encountered symptoms and their management in patients with cirrhosis.Frontiers in medicine · 2024Review
- Exploitation of multi-walled carbon nanotubes/Cu(ii)-metal organic framework based glassy carbon electrode for the determination of orphenadrine citrate.RSC advances · 2023Article
- Muscle Cramps in Outpatients with Liver Diseases in Tokyo, Japan.Medicina (Kaunas, Lithuania) · 2023Article
- Current approaches to the management of patients with cirrhotic ascites.World journal of gastroenterology · 2019Review
- [Research advances of sarcopenia in chronic liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019Article
- Pilot study of orphenadrine as a novel treatment for muscle cramps in patients with liver cirrhosis.United European gastroenterology journal · 2018Article
- Nutrition and Muscle in Cirrhosis.Journal of clinical and experimental hepatology · 2017Review
- Evaluation and management of insomnia, muscle cramps, fatigue, and itching in cirrhotic patients.Clinical liver disease · 2016Article
- Issues in the end-stage liver disease patient for which palliative care could be helpful.Clinical liver disease · 2015Review
- Muscle cramps in cirrhosis.Clinical liver diseaseArticle
- Treatment of Muscle Cramps in Patients With Cirrhosis of Liver: A Systematic Review.Journal of clinical and experimental hepatologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Muscle cramps are common in patients with liver disease and adversely influence quality of life. The exact mechanisms by which they occur remain unclear, although a number of pathophysiological events unique to liver disease may contribute. Clinical studies have identified alterations in 3 areas: nerve function, energy metabolism, and plasma volume/electrolytes. Treatments have focused on these particular areas with varied results. This review will focus on the clinical features of muscle cramps in patients with liver disease and review potential mechanisms and current therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.