ArticlePediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association2013
Reliability and validity of the TIMPSI for infants with spinal muscular atrophy type I.
Article in Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Research into the correlation between positional skull deformation and motor performance of infants aged under 4 months.BMC pediatrics · 2023Article
- Functional movement assessment with the Test of Infant Motor Performance.Journal of perinatology : official journal of the California Perinatal Association · 2021Review
- Update on Biomarkers in Spinal Muscular Atrophy.Biomarker insights · 2021Review
- Maximum bite force in patients with spinal muscular atrophy during the first year of nusinersen therapy - A pilot study.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2020Article
- Motor Function Test Reliability During the NeuroNEXT Spinal Muscular Atrophy Infant Biomarker Study.Journal of neuromuscular diseases · 2018Article
- Natural history of infantile-onset spinal muscular atrophy.Annals of neurology · 2017Article
- Developmental milestones in type I spinal muscular atrophy.Neuromuscular disorders : NMD · 2016Article
- Baseline results of the NeuroNEXT spinal muscular atrophy infant biomarker study.Annals of clinical and translational neurology · 2016Article
Corrections and comments
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Authors and funding
15 authors.
Funding
Abstract
purposeThis study examined the reliability and validity of the Test of Infant Motor Performance Screening Items (TIMPSI) in infants with type I spinal muscular atrophy (SMA).
methodsAfter training, 12 evaluators scored 4 videos of infants with type I SMA to assess interrater reliability. Intrarater and test-retest reliability was further assessed for 9 evaluators during a SMA type I clinical trial, with 9 evaluators testing a total of 38 infants twice. Relatedness of the TIMPSI score to ability to reach and ventilatory support was also examined.
resultsExcellent interrater video score reliability was noted (intraclass correlation coefficient, 0.97-0.98). Intrarater reliability was excellent (intraclass correlation coefficient, 0.91-0.98) and test-retest reliability ranged from r = 0.82 to r = 0.95. The TIMPSI score was related to the ability to reach (P ≤ .05).
conclusionThe TIMPSI can reliably be used to assess motor function in infants with type I SMA. In addition, the TIMPSI scores are related to the ability to reach, an important functional skill in children with type I SMA.
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