ReviewSurvey of ophthalmology
Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis.
Review in Survey of ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 194 citations in OpenAlex.
- Granulomatosis with polyangiitis-associated choroiditis simulating serpiginous choroiditis.American journal of ophthalmology case reports · 2026Article
- Macular serpiginous choroiditis versus macular serpiginous-like choroiditis: clinical features, outcomes and prognosis.Eye (London, England) · 2026Article
- PERSISTENT PLACOID MACULOPATHY: Long-term Outcomes and Prognostic Factors.Retina (Philadelphia, Pa.) · 2026Observational
- From white dot syndromes to primary inflammatory choriocapillaropathies (PICCPs): updating and expanding the spectrum through multimodal imaging.International journal of retina and vitreous · 2026Review
- Atypical presentation of macular serpiginous choroiditis masquerading as age related macular degeneration.American journal of ophthalmology case reports · 2026Article
- Optical coherence tomography features and visual prognosis in vitreoretinal lymphoma: a structured phenotyping study.Frontiers in medicine · 2026Article
- Relentless Placoid Chorioretinitis: A Differential Diagnosis and Management Approach in a Challenging Case.Cureus · 2025Article
- The Role of Adding Intravitreal Dexamethasone Implant to the Standard Management of Serpiginous Choroiditis for Achieving Rapid Remission: A Case Report.International medical case reports journal · 2025Article
- Article
- Presumed ocular tuberculosis - need for caution before considering anti-tubercular therapy.Eye (London, England) · 2023Article
- Retinitis Pigmentosa Masquerades: Case Series and Review of the Literature.Journal of clinical medicine · 2023Article
- Diagnosis of Optic Disc Oedema: Fundus Features, Ocular Imaging Findings, and Artificial Intelligence.Neuro-ophthalmology (Aeolus Press) · 2023Review
- Relentless placoid chorioretinitis: A review of four cases in pediatric and young adult patients with a discussion of therapeutic strategies.Frontiers in pediatrics · 2023Review
- BILATERAL SERPIGINOUS-LIKE CHORIORETINITIS ASSOCIATED WITH CILIOCHOROIDAL MELANOMA: A Clinicopathologic Correlation.Retina (Philadelphia, Pa.) · 2022Article
- Mechanisms, Pathophysiology and Current Immunomodulatory/Immunosuppressive Therapy of Non-Infectious and/or Immune-Mediated Choroiditis.Pharmaceuticals (Basel, Switzerland) · 2022Review
- The use of optical coherence tomography angiography in comparing choriocapillaris recovery between two treatment strategies for multifocal choroiditis: a pilot clinical trial.Journal of ophthalmic inflammation and infection · 2022Article
- [Serpiginous-Like Choroiditis: literature Review]Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) · 2022Review
- Clinical profile, multimodal imaging, and treatment response in macular serpiginous choroiditis.Indian journal of ophthalmology · 2022Article
- Serpiginous Choroiditis Complicated with Choroidal Neovascular Membrane Detected using Optical Coherence Tomography Angiography: A Case Series and Literature ReviewTurkish journal of ophthalmology · 2021Review
- Chlorambucil combination therapy in refractory serpiginous choroiditis: A cure?American journal of ophthalmology case reports · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Serpiginous choroiditis (SC) is a posterior uveitis displaying a geographic pattern of choroiditis, extending from the juxtapapillary choroid and intermittently spreading centrifugally. The choroiditis involves the overlying retinal pigment epithelium, and the outer retina. This intraocular inflammation typically involves both eyes in otherwise healthy, middle-aged individuals with no familial or ethnic predilection. Pathogenesis is unclear; based on limited histopathologic studies, however, favorable response to immunosuppressive agents, and the absence of association with systemic or local infectious or noninfectious diseases, an organ-specific autoimmune inflammation seems likely to be the underlying process. Patients, particularly from tuberculosis-endemic regions, may present with fundus changes simulating SC, but show evidence of active tuberculosis and/or the presence of mycobacterial DNA in the aqueous humor. This has been referred to as serpiginous-like choroiditis, but we prefer the description multifocal serpiginoid choroiditis (MSC). We present the distinguishing features of SC and infectious multifocal serpiginoid choroiditis simulating SC. The distinction is crucial to avoid unnecessarily treating SC with antimicrobial agents. Advances in diagnostic and imaging modalities can help differentiate SC from MSC. Novel local and systemic treatment approaches improve the outcome and preserve vision in SC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.