Evidence map›Paper›PMID 23540686›Full record

ArticleCell2013

Ring around the Ro-sie: RNA-mediated alterations of PNPase activity.

Brian J Geiss, Jeffrey Wilusz

Open access · bronzeAbstract readComment
In one paragraph

Article in Cell, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 94% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Brian J GeissDepartment of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA. brian.geiss@colostate.edu
Jeffrey Wilusz
Colorado State University · US

Funding

Vascular stabilization as a broad theraprutic platform for biodefenseU54AI065357 · NIAID · COLORADO STATE UNIVERSITY-FORT COLLINS · PI NUNBERG, JACK H · 2005 to 2013
$77.5M
Mechanism of Regulation of mRNA StabilityR01GM072481 · NIGMS · COLORADO STATE UNIVERSITY-FORT COLLINS · PI WILUSZ, JEFFREY · 2004 to 2011
$2.7M
NIAID NIH HHS U54 AI065357NIGMS NIH HHS R01 GM072481
6 · The paper itself

Abstract

Chen et al. demonstrate a new way by which noncoding RNAs tailor the function of multicomponent complexes. They show that a noncoding RNA interacts with an exoribonuclease, altering its substrate specificity and enzymatic activity by serving as a ribonucleoprotein scaffold and, perhaps, a gate for entry of the RNA substrate.

Identifiers

PMID23540686
PMCPMC3733347
OpenAlexW1995180414

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.