Evidence map›Paper›PMID 23540559›Full record

ArticleRedox report : communications in free radical research2013

The reliability of clinical dynamic monitoring of redox status using a new redox potential (ORP) determination method.

Lizhu Zhi, Juan Liang, Xinlei Hu, Jun Xu, Chaoheng Yu, Huawei Shao, Xuanliang Pan, Chunmao Han

Abstract read
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Article in Redox report : communications in free radical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Lizhu ZhiSecond Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China. zlizhu@yahoo.com
Juan Liang
Xinlei Hu
Jun Xu
Chaoheng Yu
Huawei Shao
Xuanliang Pan
Chunmao Han

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeQuantitative monitoring of the redox status is the foundation for redox-related treatment. The purpose of this study was to evaluate the reliability of a new depolarization curve method for plasma redox potential (ORP) monitoring.

methodsUsing the new method, we performed redox determinations for the first time under different sample-handling conditions, including redox titration experiments using KMnO4 and vitamin C and dynamic redox monitoring in burn patients. The relative ORP value (ΔORP) method (improved traditional method) was used as the reference.

resultsThe new method's better reliability, electrochemical specificity and practicability, and known group validity, which are closely associated with the redox-related pathological processes of severe burns, were confirmed. Furthermore, bidirectional change in the redox status in severe burn patients was also observed for the first time.

conclusionsThis simple, stable new method could be a better practical tool for making the dynamic monitoring of the redox status feasible and for providing useful quantitative information for the judgment of redox-related pathological process, thus improving corresponding individualized treatments that rely on quantitative adjustments to the redox status.

Indexed as

Oxidation-ReductionAbbreviated Injury ScaleAdultAscorbic AcidBlood Chemical AnalysisBurnsElectrochemistryElectrodesFemaleHumansMaleMethemoglobinMiddle AgedMonitoring, PhysiologicOxidative StressPotassium PermanganateAscorbic AcidMethemoglobinPotassium PermanganateUric Acid

Identifiers

PMID23540559
PMCPMC6837659

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.