ReviewHeart (British Cardiac Society)2013
State of the evidence: mechanical ventilation with PEEP in patients with cardiogenic shock.
Review in Heart (British Cardiac Society), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 69 citations in OpenAlex.
- Percutaneous coronary intervention assisted by invasive mechanical ventilation and intra-aortic balloon pump for acute myocardial infarction with cardiogenic shock: Retrospective cohort study and meta-analyses.Bosnian journal of basic medical sciences · 2020Pooled it
- Brazilian recommendations of mechanical ventilation 2013. Part 2.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2014Guideline
- Impact of heart rate trajectories on mortality in critically Ill patients with atrial fibrillation and heart failure: a longitudinal cohort study.BMC cardiovascular disorders · 2026Article
- Non-Invasive Respiratory Support for Acute Cardiogenic Pulmonary Edema in the Acute Care Setting.Current heart failure reports · 2025Review
- Navigating Hypoxemic Respiratory Failure in Critically Ill Cardiac Patients.JACC. Advances · 2025Review
- Management of non-Cardiac Organ Failure in cardiogenic shock.American heart journal plus : cardiology research and practice · 2025Article
- The prognostic role of tricuspid annular plane systolic excursion in critically ill patients with septic shock.Journal of anesthesia, analgesia and critical care · 2025Article
- Causes and management of impaired gas exchange in critically ill patients.BJA education · 2025Review
- Prognostic Influence of Lung Compliance in Patients with Cardiogenic Shock and Invasive Mechanical Ventilation.Reviews in cardiovascular medicine · 2024Article
- Association of Non-Invasive Positive Pressure Ventilation with Short-Term Clinical Outcomes in Patients Hospitalized for Acute Decompensated Heart Failure.Journal of clinical medicine · 2021Article
- P/FP ratio: incorporation of PEEP into the PaOAnnals of intensive care · 2021Article
- Relationship between Driving Pressure and Mortality in Ventilated Patients with Heart Failure: A Cohort Study.Canadian respiratory journal · 2021Article
- Outcomes Associated with Respiratory Failure for Patients with Cardiogenic Shock and Acute Myocardial Infarction: A Substudy of the CULPRIT-SHOCK Trial.Journal of clinical medicine · 2020Article
- A mini review of inhaled beta 2 agonists in acute decompensated heart failure requiring respiratory support.Pulmonary and critical care medicine · 2019Article
- Role of High-flow Nasal Oxygen Therapy in Cases with Pulmonary Hypertension in an Intensive Care Unit Setting.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2019Article
- Pulmonary Capillary Hemorrhage Induced by Acoustic Radiation Force Impulse Shear Wave Elastography in Ventilated Rats.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2019Article
- Positive Pressure Ventilation in the Cardiac Intensive Care Unit.Journal of the American College of Cardiology · 2018Review
- Pulmonary Capillary Hemorrhage Induced by Diagnostic Ultrasound in Ventilated Rats.Ultrasound in medicine & biology · 2018Article
- Metastatic leiomyosarcoma presenting as a lung mass with left atrial extension: case report and anesthetic management.Therapeutics and clinical risk management · 2018Article
- Management of Mechanical Ventilation in Decompensated Heart Failure.Journal of cardiovascular development and disease · 2016Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
The need to provide invasive mechanical ventilatory support to patients with myocardial infarction and acute left heart failure is common. Despite the large number of patients requiring mechanical ventilation in this setting, there are remarkably few data addressing the ideal mode of respiratory support in such patients. Although there is near universal acceptance regarding the use of non-invasive positive pressure ventilation in patients with acute pulmonary oedema, there is more concern with invasive positive pressure ventilation owing to its more significant haemodynamic impact. Positive end-expiratory pressure (PEEP) is almost universally applied in mechanically ventilated patients due to benefits in gas exchange, recruitment of alveolar units, counterbalance of hydrostatic forces leading to pulmonary oedema and maintenance of airway patency. The limited available clinical data suggest that a moderate level of PEEP is safe to use in severe left ventricular (LV) dysfunction and cardiogenic shock, and may provide haemodynamic benefits as well in LV failure which exhibits afterload-sensitive physiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.