Evidence map›Paper›PMID 23539523›Full record

ArticleWorld journal of gastroenterology2013

Infliximab induces remission in cryptogenic multifocal ulcerous stenosing enteritis: first case.

Heiko De Schepper, Elisabeth Macken, Veerle Van Marck, Maarten Spinhoven, Paul Pelckmans, Tom Moreels

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of gastroenterology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. MUSings on a Crohn's Disease Diagnosis.Digestive diseases and sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Heiko De SchepperDepartment of Gastroenterology and Hepatology, Antwerp University Hospital, B-2650 Edegem-Antwerp, Belgium. heiko.de.schepper@uza.be
Elisabeth Macken
Veerle Van Marck
Maarten Spinhoven
Paul Pelckmans
Tom Moreels
Antwerp University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 29-year-old patient with a history of abdominal pain and vomiting. Based on wireless video capsule findings he was previously diagnosed with ileal Crohn's disease at a different institution, although the clinical and radiological picture was not typical and the response to corticosteroids was poor. We performed a single-balloon enteroscopy showing a short, ulcerous stenosis 50 cm proximal from Bauhin's valve. The endoscopic and clinical histopathological findings were compatible with cryptogenic multifocal ulcerous stenosing enteritis (CMUSE). High dose corticosteroids were again started, without effect. The monoclonal tumor necrosis factor-α (TNF-α) antibody infliximab was added to the medical therapy. After induction therapy, both clinical and endoscopic amelioration was obtained. Larger case studies are needed to confirm the efficacy of TNF-α inhibition in steroid refractory CMUSE.

Indexed as

Adrenal Cortex HormonesAdultAntibodies, MonoclonalAnti-Inflammatory AgentsCapsule EndoscopyConstriction, PathologicCrohn DiseaseDiagnostic ErrorsDrug SubstitutionGastrointestinal AgentsHumansIleitisInfliximabIntestinal ObstructionMalePredictive Value of TestsAdrenal Cortex HormonesAntibodies, MonoclonalAnti-Inflammatory AgentsGastrointestinal AgentsInfliximabTumor Necrosis Factor-alphaCryptogenic multifocal ulcerous stenosing enteritisInflammatory bowel diseaseInfliximabIntestinal ulcerationStenosis

Identifiers

PMID23539523
PMCPMC3602486
OpenAlexW99981455

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.