ArticleClinical orthopaedics and related research2013
Is the bone-bonding ability of a cementless total hip prosthesis enhanced by alkaline and heat treatments?
Article in Clinical orthopaedics and related research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 39 citations in OpenAlex.
- Minimum ten-year results of total hip arthroplasty using an alkali- and heat-treated titanium Zweymüller-type stem.International orthopaedics · 2026Article
- Advanced surface engineering of titanium materials for biomedical applications: From static modification to dynamic responsive regulation.Bioactive materials · 2023Review
- High Subsidence Rate After Primary Total Hip Arthroplasty Using a Zweymüller-type Noncemented Implant With a Matte Surface.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2022Article
- Bioactivation Treatment with Mixed Acid and Heat on Titanium Implants Fabricated by Selective Laser Melting Enhances Preosteoblast Cell Differentiation.Nanomaterials (Basel, Switzerland) · 2021Article
- The Use of Simulated Body Fluid (SBF) for Assessing Materials Bioactivity in the Context of Tissue Engineering: Review and Challenges.Biomimetics (Basel, Switzerland) · 2020Review
- Two-in-One Biointerfaces-Antimicrobial and Bioactive Nanoporous Gallium Titanate Layers for Titanium Implants.Nanomaterials (Basel, Switzerland) · 2017Article
- New Ti-Alloys and Surface Modifications to Improve the Mechanical Properties and the Biological Response to Orthopedic and Dental Implants: A Review.BioMed research international · 2016Review
- In vivo study of the early bone-bonding ability of Ti meshes formed with calcium titanate via chemical treatments.Journal of materials science. Materials in medicine · 2015Article
- Growth of Novel Ceramic Layers on Metals via Chemical and Heat Treatments for Inducing Various Biological Functions.Frontiers in bioengineering and biotechnology · 2015Review
- Bioactive titanate layers formed on titanium and its alloys by simple chemical and heat treatments.The open biomedical engineering journal · 2015Article
- Antibacterial and bioactive calcium titanate layers formed on Ti metal and its alloys.Journal of materials science. Materials in medicine · 2014Article
- Effect of anodization and alkali-heat treatment on the bioactivity of titanium implant material (an in vitro study).Journal of International Society of Preventive & Community DentistryArticle
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundCementless total hip arthroplasty (THA) implants using alkaline and heat treatments were developed to enhance bone bonding. Although bone-bonding ability of the alkali- and heat-treated titanium surface has been demonstrated in animal studies, it remains unknown whether it enhances or provides durable bone bonding in humans. QUESTIONS/PURPOSES: We therefore (1) determined long-term survivorship, function, and radiographic signs of failure of fixation of alkali- and heat-treated THA implants; and (2) histologically examined their bone-bonding ability in two human retrievals.
methodsWe retrospectively reviewed 58 patients who underwent 70 primary THAs, of whom 67 were available for minimum followup of 8 years (average, 10 years; range, 8-12 years). Survival rate was calculated. Hip function was evaluated using the Japan Orthopaedic Association (JOA) hip scores, and radiographic signs of implant failure were determined from anteroposterior radiographs. Two retrieved implants were investigated histologically.
resultsUsing revision for any reason as the end point, the overall survival rate was 98% (95% confidence interval, 96%-100%) at 10 years. The patients' average JOA hip scores improved from 47 points preoperatively to 91 points at the time of the last followup. No implant had radiographic signs of loosening. Histologically we observed bone in the pores 2 weeks after implantation in one specimen and apparently direct bonding between bone and the titanium surface in its deep pores 8 years after implantation.
conclusionsCementless THA implants with alkaline and heat treatments showed a high survival rate. Further study is required to determine whether the treatment enhances direct bone bonding.
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