ArticleAnalytical and bioanalytical chemistry2013
Mass spectrometry imaging for biomedical applications.
Article in Analytical and bioanalytical chemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Quantitative MALDI-MSI Workflow for Lipids with a LC-MS-Based Quality Control Pipeline.ACS measurement science au · 2026Article
- Efficient metabolic fingerprinting profiling of extracellular vesicles for precise cancer diagnosis and treatment monitoring.Materials today. Bio · 2025Article
- A laboratory-friendly protocol for freeze-drying sample preparation in ToF-SIMS single-cell imaging.Frontiers in chemistry · 2025Article
- Accumulation of Bioactive Lipid Species in LPS-Induced Neuroinflammation Models Analysed with Multi-Modal Mass Spectrometry Imaging.International journal of molecular sciences · 2024Article
- GeenaR: A Web Tool for Reproducible MALDI-TOF Analysis.Frontiers in genetics · 2021Article
- Antireflection Surfaces for Biological Analysis Using Laser Desorption Ionization Mass Spectrometry.Research (Washington, D.C.) · 2018Article
- Label-free molecular imaging of the kidney.Kidney international · 2017Review
- Ambient Ionization and Miniature Mass Spectrometry Systems for Disease Diagnosis and Therapeutic Monitoring.Theranostics · 2017Review
- Design of portable mass spectrometers with handheld probes: aspects of the sampling and miniature pumping systems.Journal of the American Society for Mass Spectrometry · 2015Article
- In Situ characterization of proteins using laserspray ionization on a high-performance MALDI-LTQ-Orbitrap mass spectrometer.Journal of the American Society for Mass Spectrometry · 2014Article
- Mapping antiretroviral drugs in tissue by IR-MALDESI MSI coupled to the Q Exactive and comparison with LC-MS/MS SRM assay.Journal of the American Society for Mass Spectrometry · 2014Article
- Development of miniature mass spectrometry systems for bioanalysis outside the conventional laboratories.Bioanalysis · 2014Article
- Development of a mass spectrometry sampling probe for chemical analysis in surgical and endoscopic procedures.Analytical chemistry · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The development of technologies for mass spectrometry imaging is of substantial research interest. Mass spectrometry is potentially capable of providing highly specific information about the distribution of compounds in tissues, with high sensitivity. The in-situ analysis needed for tissue imaging requires MS to be performed under conditions different from the traditional ones, typically with intensive sample preparation and optimized for pharmaceutical applications. In this paper we critically review the current status of MS imaging with different methods of sample ionization and discuss the 3D and quantitative imaging capabilities which need further development, the importance of the multi-modal imaging, and the balance between the pursuit of high-resolution imaging and the practical application of MS imaging in biomedicine.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.