ArticleJournal of computational neuroscience2013
A working memory model for serial order that stores information in the intrinsic excitability properties of neurons.
Article in Journal of computational neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Cognitive Control.Annual review of psychology · 2025Review
- Predicted utility modulates working memory fidelity in the brain.Cortex; a journal devoted to the study of the nervous system and behavior · 2023Article
- Superresolution imaging reveals activity-dependent plasticity of axon morphology linked to changes in action potential conduction velocity.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Spike-Based Bayesian-Hebbian Learning of Temporal Sequences.PLoS computational biology · 2016Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Models for temporary information storage in neuronal populations are dominated by mechanisms directly dependent on synaptic plasticity. There are nevertheless other mechanisms available that are well suited for creating short-term memories. Here we present a model for working memory which relies on the modulation of the intrinsic excitability properties of neurons, instead of synaptic plasticity, to retain novel information for periods of seconds to minutes. We show that it is possible to effectively use this mechanism to store the serial order in a sequence of patterns of activity. For this we introduce a functional class of neurons, named gate interneurons, which can store information in their membrane dynamics and can literally act as gates routing the flow of activations in the principal neurons population. The presented model exhibits properties which are in close agreement with experimental results in working memory. Namely, the recall process plays an important role in stabilizing and prolonging the memory trace. This means that the stored information is correctly maintained as long as it is being used. Moreover, the working memory model is adequate for storing completely new information, in time windows compatible with the notion of "one-shot" learning (hundreds of milliseconds).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.