Evidence map›Paper›PMID 23539003›Full record

ArticleAnais brasileiros de dermatologia

Low level laser therapy (AlGaInP) applied at 5J/cm2 reduces the proliferation of Staphylococcus aureus MRSA in infected wounds and intact skin of rats.

Daniela Conceição Gomes Gonçalves e Silva, Helio Plapler, Mateus Matiuzzi da Costa, Silvio Romero Gonçalves e Silva, Maria da Conceição Aquino de Sá, Benedito Sávio Lima e Silva

Open access · goldAbstract read
In one paragraph

Article in Anais brasileiros de dermatologia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Association of Primate Veterinarians Guidelines For Mrsa Infections in Nonhuman Primates in Biomedical Research.Journal of the American Association for Laboratory Animal Science : JAALAS · 2019
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 1 country.

Daniela Conceição Gomes Gonçalves e SilvaFaculdade Inspirar Petrolina, Petrolina, PE, Brazil. danielaftgomes@hotmail.com
Helio Plapler
Mateus Matiuzzi da Costa
Silvio Romero Gonçalves e Silva
Maria da Conceição Aquino de Sá
Benedito Sávio Lima e Silva
Universidade Federal do Vale do São Francisco · BRFaculdade Brasil · BRUniversidade de Pernambuco · BRUniversidade Federal de Santa Maria · BRUniversidade Federal de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLaser therapy is a low cost, non-invasive procedure with good healing results. Doubts exist as to whether laser therapy action on microorganisms can justify research aimed at investigating its possible effects on bacteria-infected wounds.

objectiveTo assess the effect of low intensity laser on the rate of bacterial contamination in infected wounds in the skin of rats.

methodsAn experimental study using 56 male Wistar rats. The animals were randomly divided into eight groups of seven each. Those in the "infected" groups were infected by Staphylococcus aureus MRSA in the dorsal region. Red laser diode (AlGaInP) 658nm, 5J/cm2 was used to treat the animals in the "treated" groups in scan for 3 consecutive days. Samples were drawn before inoculating bacteria and following laser treatment. For statistical analysis we used the nonparametric Wilcoxon (paired data) method with a significance level of p <0.05.

resultsThe statistical analysis of median values showed that the groups submitted to laser treatment had low bacterial proliferation.

conclusionThe laser (AlGaInP), with a dose of 5J/cm2 in both intact skin and in wounds of rats infected with Staphylococcus aureus MRSA, is shown to reduce bacterial proliferation.

Indexed as

Analysis of VarianceAnimalsColony Count, MicrobialDisease Models, AnimalLow-Level Light TherapyMaleMethicillin-Resistant Staphylococcus aureusRadiation DosageRandom AllocationRatsRats, WistarStaphylococcal InfectionsStatistics, NonparametricWound HealingWound Infection

Identifiers

PMID23539003
PMCPMC3699931
OpenAlexW2043935322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.