Evidence map›Paper›PMID 23538918›Full record

Trial reportBMJ (Clinical research ed.)2013

Effect of routine controlled cord traction as part of the active management of the third stage of labour on postpartum haemorrhage: multicentre randomised controlled trial (TRACOR).

Catherine Deneux-Tharaux, Loic Sentilhes, Françoise Maillard, Emmanuel Closset, Delphine Vardon, Jacques Lepercq, François Goffinet

Erratum issued 2 registry-linked trialsOpen access · hybridAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in BMJ (Clinical research ed.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 2 registered trials, which are not on this map. Cited by 21 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 5 pooled it
17.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01044082 nacompletednot on this map

Impact of Controlled Cord Traction During the Third Stage of Labour on the Incidence of Post Partum Haemorrhage

TypeinterventionalSponsorAssistance Publique - Hôpitaux de ParisRan2010 to 2012Enrolled4,382ConditionsPostpartum Haemorrhage, Immediate Postpartum HemorrhageArmscontrolled cord traction, Clinical signs of placental separation
NCT03069859 phase2unknown statusnot on this mapstarted 2018, after this paper: background citation

Prophylactic Use of Tranexamic Acid for Preventing Postpartum Hemorrhage: A Randomized, Double-blinded, Placebo-controlled Pilot Trial

TypeinterventionalSponsorSunnybrook Health Sciences CentreRan2018 to 2022Enrolled31ConditionsPost Partum HemorrhageArmsTXA (1g), Placebo (0.9% saline)
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 5 syntheses or guidelines pooled it, 95 citations in OpenAlex.

  1. Pooled it
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  3. Active versus expectant management for women in the third stage of labour.The Cochrane database of systematic reviews · 2019
    Pooled it
  4. Tranexamic acid for preventing postpartum haemorrhage.The Cochrane database of systematic reviews · 2015
    Pooled it
  5. Controlled cord traction for the third stage of labour.The Cochrane database of systematic reviews · 2015
    Pooled it
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Catherine Deneux-TharauxINSERM U953, Epidemiologic Research in Perinatal, Women's, and Children's Health, Pierre et Marie Curie University, Paris, France. catherine.deneux-tharaux@inserm.fr
Loic Sentilhes
Françoise Maillard
Emmanuel Closset
Delphine Vardon
Jacques Lepercq
François Goffinet
Assistance Publique – Hôpitaux de Paris · FRSorbonne Université · FRHôpital Jeanne de Flandre · FRUniversité d'Angers · FRUniversité de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the impact of controlled cord traction on the incidence of postpartum haemorrhage and other characteristics of the third stage of labour in a high resource setting.

designRandomised controlled trial.

settingFive university hospital maternity units in France.

participantsWomen aged 18 or more with a singleton fetus at 35 or more weeks' gestation and planned vaginal delivery.

interventionsWomen were randomly assigned to management of the third stage of labour by controlled cord traction or standard placenta expulsion (awaiting spontaneous placental separation before facilitating expulsion). Women in both arms received prophylactic oxytocin just after birth.

main outcome measureIncidence of postpartum haemorrhage ≥ 500 mL as measured in a collector bag.

resultsThe incidence of postpartum haemorrhage did not differ between the controlled cord traction arm (9.8%, 196/2005) and standard placenta expulsion arm (10.3%, 206/2008): relative risk 0.95 (95% confidence interval 0.79 to 1.15). The need for manual removal of the placenta was significantly less frequent in the controlled cord traction arm (4.2%, 85/2033) compared with the standard placenta expulsion arm (6.1%, 123/2024): relative risk 0.69, 0.53 to 0.90); as was third stage of labour of more than 15 minutes (4.5%, 91/2030 and 14.3%, 289/2020, respectively): relative risk 0.31, 0.25 to 0.39. Women in the controlled cord traction arm reported a significantly lower intensity of pain and discomfort during the third stage than those in the standard placenta expulsion arm. No uterine inversion occurred in either arm.

conclusionsIn a high resource setting, the use of controlled cord traction for the management of placenta expulsion had no significant effect on the incidence of postpartum haemorrhage and other markers of postpartum blood loss. Evidence to recommend routine controlled cord traction for the management of placenta expulsion to prevent postpartum haemorrhage is therefore lacking.

trial registrationClinicalTrials.gov NCT01044082.

Indexed as

Labor Stage, ThirdUmbilical CordAdolescentAdultFemaleFranceHumansLabor, ObstetricPlacentaPostpartum HemorrhagePregnancyTreatment OutcomeYoung Adult

Identifiers

PMID23538918
PMCPMC3610557
OpenAlexW2058130718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.