ArticleAJNR. American journal of neuroradiology
Histopathologic evaluation of arterial wall response to 5 neurovascular mechanical thrombectomy devices in a swine model.
Article in AJNR. American journal of neuroradiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 1 of them a synthesis that pooled it.
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Who cites it
42 citing papers in PubMed, 1 synthesis or guideline pooled it, 108 citations in OpenAlex.
- Large animals in neurointerventional research: A systematic review on models, techniques and their application in endovascular procedures for stroke, aneurysms and vascular malformations.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2019Pooled it
- Adhesion of vessel wall to stentriever during combined technique for mechanical thrombectomy in acute ischemic stroke: A histomorphological study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2026Article
- Is first-pass effect a meaningful metric to evaluate thrombectomy technologies?Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- In Vitro Assessment of Vascular Injury following Stent Retriever Retraction in Clinically Relevant Endothelialized Silicone Models.AJNR. American journal of neuroradiology · 2025Article
- The prognostic significance of hyperdense middle cerebral artery sign in cardioembolic stroke patients undergoing mechanical thrombectomy.BMC neurology · 2025Article
- Vascular injury and occurrence of microthrombi after endovascular therapy for acute ischaemic stroke in a thromboembolic model.BMJ neurology open · 2025Article
- Review: Preclinical Models of Large-Vessel Occlusion Stroke.Stroke (Hoboken, N.J.) · 2024Review
- The correlation between intracranial arterial calcification and the outcome of reperfusion therapy.Annals of clinical and translational neurology · 2023Article
- Forced suction thrombectomy in patients with acute ischemic stroke using the SOFIA Plus device.Journal of cerebrovascular and endovascular neurosurgery · 2022Article
- Preclinical Large Vessel Occlusion Stroke Model: Capybaras (Stroke (Hoboken, N.J.) · 2022Article
- Histological evaluation of acute ischemic stroke thrombi may indicate the occurrence of vessel wall injury during mechanical thrombectomy.Journal of neurointerventional surgery · 2022Article
- Observational
- Reperfusion therapy in a patient with early recurrence of ischemic stroke.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022Article
- Article
- High-resolution vessel wall imaging after mechanical thrombectomy.The neuroradiology journal · 2021Article
- Preclinical testing platforms for mechanical thrombectomy in stroke: a review on phantoms, in-vivo animal, and cadaveric models.Journal of neurointerventional surgery · 2021Review
- Direct Stenting of Intracranial Atherosclerosis-related Acute Large Vessel Occlusion.Clinical neuroradiology · 2021Article
- Novel Human Acute Ischemic Stroke Blood Clot Analogs for In Vitro Thrombectomy Testing.AJNR. American journal of neuroradiology · 2021Article
- Interventional stroke treatment - Is it also safe for arteries? Looking at thrombectomy wall damage through clot histology.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2021Article
- Histopathologic findings of vascular damage after mechanical thrombectomy using stent retriever in canine models.Journal of thrombosis and thrombolysis · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeFive commercial devices are available for mechanical thrombectomy in acute ischemic stroke. This study evaluated and compared the resultant arterial damage from these devices. MATERIALS AND
methodsWall damage after 4 wall-contact devices (the Merci retriever, Catch thromboembolectomy system, and Solitaire FR revascularization devices of 4 and 6 mm) and 1 aspiration device (the Penumbra System) was evaluated in the superficial femoral arteries of 20 male swine. Each device was tested with and without intraluminal clot. Twenty control vessels were not subjected to any intervention. Acute histopathologic changes were evaluated.
resultsIn the device samples, endothelial denudation (72.8 ± 29.4% versus 0.9 ± 1.9%, P < .0001), medial layer edema (52 ± 35.9% versus 18.1 ± 27.8%, P = .004), and mural thrombus (5.3 ± 14.2% versus 0%, P = .05) were found to a greater extent compared with the control samples. The aspiration device provoked more intimal layer (100 ± 79.1% versus 58.8 ± 48.9%, P = .27) and medial layer (75 ± 35.4% versus 46.3 ± 34.8%, P = .13) edema than the wall-contact devices.
conclusionsAll devices caused vascular injuries extending into the medial layer. The aspiration device was associated with more intimal and medial layer edema, compared with the wall-contact devices except for the Catch thromboembolectomy system.
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