ArticleDiagnostic microbiology and infectious disease2013
Evaluation of 10 serological assays for diagnosing Mycoplasma pneumoniae infection.
Article in Diagnostic microbiology and infectious disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Immunochromatography for the diagnosis of Mycoplasma pneumoniae infection: A systematic review and meta-analysis.PloS one · 2020Pooled it
- Exploiting the Clinical Potential of a Chemiluminescent Probe forChemical & biomedical imaging · 2026Article
- Emergence of Clinically Macrolide-UnresponsiveAntibiotics (Basel, Switzerland) · 2026Article
- Diagnostic Accuracy of Serological Tests forAnnals of laboratory medicine · 2026Article
- Zirconium-based metal-organic frameworks for pathogen detection.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026Review
- Clinical Diagnostic Prediction Model For Mycoplasma pneumoniae Pneumonia in Children.Infection and drug resistance · 2025Article
- Evaluation of the CARDS toxin and its fragment for the serodiagnosis of Mycoplasma pneumoniae infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Seropositive anti-MOG antibody-associated acute disseminated encephalomyelitis (ADEM): a sequelae ofBMJ case reports · 2020Article
- Use of a rapid recombinase-aided amplification assay for Mycoplasma pneumoniae detection.BMC infectious diseases · 2020Article
- Comparison of enzyme-linked immunosorbent assay with indirect immunofluorescence assay for the diagnosis of Mycoplasma pneumoniae infection.Journal of clinical laboratory analysis · 2019Article
- Early Diagnosis ofFrontiers in pediatrics · 2019Article
- Evaluation of the VircliaJournal of clinical laboratory analysis · 2018Article
- A sensitive and rapid immunoassay for Mycoplasma pneumoniae in children with pneumonia based on single-walled carbon nanotubes.Scientific reports · 2017Article
- Mycoplasma pneumoniae from the Respiratory Tract and Beyond.Clinical microbiology reviews · 2017Review
- Article
- Role of Serum Mycoplasma pneumoniae IgA, IgM, and IgG in the Diagnosis of Mycoplasma pneumoniae-Related Pneumonia in School-Age Children and Adolescents.Clinical and vaccine immunology : CVI · 2017Article
- Antibody Response to Mycoplasma pneumoniae: Protection of Host and Influence on Outbreaks?Frontiers in microbiology · 2016Review
- Mycoplasma pneumoniae: Current Knowledge on Nucleic Acid Amplification Techniques and Serological Diagnostics.Frontiers in microbiology · 2016Review
- Evaluation of five real-time PCR assays for detection of Mycoplasma pneumoniae.Journal of clinical microbiology · 2014Article
- Universal newborn screening for congenital CMV infection: what is the evidence of potential benefit?Reviews in medical virology · 2014Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, the performance of 10 serological assays for the diagnosis of Mycoplasma pneumoniae infection was evaluated. A total of 145 sera from 120 patients were tested. They were obtained from patients who were serologically positive for M. pneumoniae infection as well as from patients who were infected with micro-organisms that may cause interstitial pneumonia. The following assays were utilized: SeroMP IgM and IgG, SeroMP recombinant IgM, IgA and IgG, Liaison M. pneumoniae IgM and IgG and M. pneumoniae IgM, IgA and IgG ELISA Medac. The SeroMP Recombinant and Liaison assays both showed low IgM specificity, and crossreactivity was mainly observed in groups of patients with acute cytomegalovirus and Epstein-Barr virus infections. For IgA, the Medac assay was less specific than the SeroMP Recombinant assay. Discrepancies between the four tests were observed in IgG analyses, and due to the lack of a gold standard, 22 results were removed prior to determining the sensitivity and specificity. Therefore, the overall performance of IgG assays may be overstated; nevertheless, the SeroMP assay demonstrated a lack of sensitivity. The seroprevalence of IgG appears to be very low, raising concerns regarding whether the serological techniques can detect IgG levels over time. Serology remains a biological tool of choice for diagnosing M. pneumoniae infection, but improvement and standardization of the assays are needed, particularly for the determination of IgG.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.