Evidence map›Paper›PMID 23536809›Full record

ArticlePloS one2013

United states acculturation and cancer patients' end-of-life care.

Alexi A Wright, Heather Stieglitz, Yankel M Kupersztoch, M Elizabeth Paulk, Yookyung Kim, Ingrid T Katz, Francisco Munoz, Rachel B Jimenez, Jan Mutchler, Lorna Rivera and 2 more

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
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  8. Review
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  11. Association between Chinese or South Asian ethnicity and end-of-life care in Ontario, Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020
    Observational
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 1 country.

Alexi A WrightDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America.
Heather Stieglitz
Yankel M Kupersztoch
M Elizabeth Paulk
Yookyung Kim
Ingrid T Katz
Francisco Munoz
Rachel B Jimenez
Jan Mutchler
Lorna Rivera
Anthony L Back
Holly G Prigerson
Dana-Farber Cancer Institute · USHarvard University · USThe University of Texas Southwestern Medical Center · USUniversity of Massachusetts Boston · USParkland Center For Clinical Innovation · USPomona Valley Hospital Medical Center · USUniversity of Pittsburgh · USUniversity of Washington · US

Funding

U Mass Boston / DFHCC U54 Partnership (1 of 2)U54CA156732 · NCI · DANA-FARBER CANCER INST · PI WENDY Beth LONDON · 2010 to 2026
$25.6M
Quality of Death: Ethnic and Psychosocial InfluencesR01CA106370 · NCI · YALE UNIVERSITY · PI PRIGERSON, HOLLY GWEN · 2004 to 2015
$4.1M
Psychiatric Disorder in Dying Patients &Their SurvivorsR01MH063892 · NIMH · YALE UNIVERSITY · PI JACOBS, SELBY C · 2002 to 2005
$1.9M
HIV Treatment Refusal Among Adults Presenting for Testing in Soweto, South AfricaK23MH097667 · NIMH · BRIGHAM AND WOMEN'S HOSPITAL · PI KATZ, INGRID T. · 2012 to 2016
$922k
NCI NIH HHS CA 106370NCI NIH HHS CA 156732NCI NIH HHS R01 CA106370NCI NIH HHS U54 CA156732NIMH NIH HHS K23 MH097667NIMH NIH HHS MH63892NIMH NIH HHS R01 MH063892
6 · The paper itself

Abstract

backgroundCulture shapes how people understand illness and death, but few studies examine whether acculturation influences patients' end-of-life treatment preferences and medical care. METHODS AND

findingsIn this multi-site, prospective, longitudinal cohort study of terminally-ill cancer patients and their caregivers (n = 171 dyads), trained interviewers administered the United States Acculturation Scale (USAS). The USAS is a 19-item scale developed to assess the degree of "Americanization" in first generation or non-US born caregivers of terminally-ill cancer patients. We evaluated the internal consistency, concurrent, criterion, and content validity of the USAS. We also examined whether caregivers' USAS scores predicted patients' communication, treatment preferences, and end-of-life medical care in multivariable models that corrected for significant confounding influences (e.g. education, country of origin, English proficiency). The USAS measure was internally consistent (Cronbach α = 0.98); and significantly associated with US birthplace (r = 0.66, P<0.0001). USAS scores were predictive of patients' preferences for prognostic information (AOR = 1.31, 95% CI:1.00-1.72), but not comfort asking physicians' questions about care (AOR 1.23, 95% CI:0.87-1.73). They predicted patients' preferences for feeding tubes (AOR = 0.68, 95% CI:0.49-0.99) and wish to avoid dying in an intensive care unit (AOR = 1.36, 95% CI:1.05-1.76). Scores indicating greater acculturation were also associated with increased odds of patient participation in clinical trials (AOR = 2.20, 95% CI:1.28-3.78), compared with lower USAS scores, and greater odds of patients receiving chemotherapy (AOR = 1.59, 95% CI:1.20-2.12).

conclusionThe USAS is a reliable and valid measure of "Americanization" associated with advanced cancer patients' end-of-life preferences and care. USAS scores indicating greater caregiver acculturation were associated with increased odds of patient participation in cancer treatment (chemotherapy, clinical trials) compared with lower scores. Future studies should examine the effects of acculturation on end-of-life care to identify patient and provider factors that explain these effects and targets for future interventions to improve care (e.g., by designing more culturally-competent health education materials).

Indexed as

AcculturationTerminal CareAdultAgedCaregiversFemaleHealth Care SurveysHumansMaleMiddle AgedNeoplasmsPatient PreferencePhysician-Patient RelationsProspective StudiesReproducibility of ResultsRisk Factors

Identifiers

PMID23536809
PMCPMC3594172
OpenAlexW2113147266

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.