ArticleJournal of clinical microbiology2013
Absence of Mycobacterium intracellulare and presence of Mycobacterium chimaera in household water and biofilm samples of patients in the United States with Mycobacterium avium complex respiratory disease.
Article in Journal of clinical microbiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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Who cites it
55 citing papers in PubMed, 144 citations in OpenAlex.
- Spinal infections.Frontiers in neuroscience · 2026Review
- Global lineages of non-tuberculous mycobacteria in residential water samples from Germany.BMC microbiology · 2025Article
- Detection of Mycobacterium chimaera in medical device water samples by customised real time PCR using a InGenius platform.Scientific reports · 2024Article
- Isolation and identification of non-tuberculous mycobacteria from aquarium fish in Ilam, Iran.Journal of clinical tuberculosis and other mycobacterial diseases · 2024Article
- Non-Tuberculous Mycobacteria: Single Center Analyses of Risk Factors, Management and Mortality Outcomes of Adults with HIV.Diagnostics (Basel, Switzerland) · 2024Article
- The State-of-the-Art ofHealthcare (Basel, Switzerland) · 2024Review
- Single-cell transcriptomics by clinical course of Mycobacterium avium complex pulmonary disease.Scientific reports · 2024Article
- Building size and disinfectant type influence the detection and concentration of Mycobacterium spp. in hot water plumbing.The Science of the total environment · 2024Article
- Biofilm prevention concentration of clarithromycin against clinically relevant species of nontuberculous mycobacteria.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2024Article
- Investigating the Origin of Mycobacterium chimaera Contamination in Heater-Cooler Units: Integrated Analysis with Fourier Transform Infrared Spectroscopy and Whole-Genome Sequencing.Microbiology spectrum · 2022Article
- Biofilm infection of a central venous port-catheter caused by Mycobacterium avium complex in an immunocompetent child with cystic fibrosis.BMC infectious diseases · 2022Article
- Occurrence revisited: Mycobacterium avium and Mycobacterium intracellulare in potable water in the USA.Applied microbiology and biotechnology · 2022Article
- Modulating macrophage function to reinforce host innate resistance againstFrontiers in immunology · 2022Review
- Population Genomics and Inference of Mycobacterium avium Complex Clusters in Cystic Fibrosis Care Centers, United States.Emerging infectious diseases · 2021Article
- Article
- The Association between Behavioral Risk Factors and Nontuberculous Mycobacterial Pulmonary Disease.Yonsei medical journal · 2021Article
- Validation of a Novel Diagnostic Approach Combining the VersaTREK™ System for Recovery and Real-Time PCR for the Identification ofMicroorganisms · 2021Article
- Identification of Nontuberculous Mycobacteria in Patients with Pulmonary Diseases in Gyeongnam, Korea, Using Multiplex PCR and Multigene Sequence-Based Analysis.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2021Article
- Risk Management in the New Frontier of Professional Liability for Nosocomial Infection: Review of the Literature on Mycobacterium Chimaera.International journal of environmental research and public health · 2020Review
- Outcome of shorter treatment duration in non-cavitary nodular bronchiectaticJournal of thoracic disease · 2020Article
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent studies have shown that respiratory isolates from pulmonary disease patients and household water/biofilm isolates of Mycobacterium avium could be matched by DNA fingerprinting. To determine if this is true for Mycobacterium intracellulare, household water sources for 36 patients with Mycobacterium avium complex (MAC) lung disease were evaluated. MAC household water isolates from three published studies that included 37 additional MAC respiratory disease patients were also evaluated. Species identification was done initially using nonsequencing methods with confirmation by internal transcribed spacer (ITS) and/or partial 16S rRNA gene sequencing. M. intracellulare was identified by nonsequencing methods in 54 respiratory cultures and 41 household water/biofilm samples. By ITS sequencing, 49 (90.7%) respiratory isolates were M. intracellulare and 4 (7.4%) were Mycobacterium chimaera. In contrast, 30 (73%) household water samples were M. chimaera, 8 (20%) were other MAC X species (i.e., isolates positive with a MAC probe but negative with species-specific M. avium and M. intracellulare probes), and 3 (7%) were M. avium; none were M. intracellulare. In comparison, M. avium was recovered from 141 water/biofilm samples. These results indicate that M. intracellulare lung disease in the United States is acquired from environmental sources other than household water. Nonsequencing methods for identification of nontuberculous mycobacteria (including those of the MAC) might fail to distinguish closely related species (such as M. intracellulare and M. chimaera). This is the first report of M. chimaera recovery from household water. The study underscores the importance of taxonomy and distinguishing the many species and subspecies of the MAC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.