ArticleHigh blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension2013
2012 consensus document of the Italian Society of Hypertension (SIIA): strategies to improve blood pressure control in Italy: from global cardiovascular risk stratification to combination therapy.
Article in High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 10 of them syntheses that pooled it.
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Who cites it
41 citing papers in PubMed, 10 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Rationale for the Use of Fixed Combination Therapies with Angiotensin Converting Enzyme Inhibitors and Beta-Blockers in Patients with Essential Hypertension and High Cardiovascular Risk: A Consensus Document from the Italian Society of Arterial Hypertension (Siia) and the Italian Society of Cardiovascular Prevention (SIPREC).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Guideline
- Systematic Review Article: New Drug Strategies for Treating Resistant Hypertension-the Importance of a Mechanistic, Personalized Approach.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2024Pooled it
- Personalised Single-Pill Combination Therapy in Hypertensive Patients: An Update of a Practical Treatment Platform.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2017Guideline
- Clinical management of drug-induced hypertension: 2013 Practical Recommendations of the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2014Guideline
- Clinical management of primary aldosteronism: 2013 Practical Recommendations of the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2014Guideline
- Echocardiography in hypertension: practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Clinical management of renovascular hypertension: practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Clinical management of resistant hypertension: practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Clinical management of coronary heart disease in hypertension : practical recommendations from the Italian Society of Hypertension (SIIA).High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Clinical management of hypertension in pregnancy. Practical recommendations from the Italian Society of Hypertension (SIIA). [corrected].High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2013Guideline
- Home Blood Pressure and Telemedicine: A Modern Approach for Managing Hypertension During and After COVID-19 Pandemic.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2022Review
- Single-pill fixed-dose drug combinations to reduce blood pressure: the right pill for the right patient.Therapeutic advances in chronic disease · 2022Review
- Hypertension Management and Control in Italy: A Real-World Survey in Elderly Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Real-world Antihypertensive Treatment Patterns, Treatment Adherence, and Blood Pressure Control in the Elderly: An Italian Awareness-raising Campaign on Hypertension by Senior Italia FederAnziani, the Italian Society of Hypertension and the Italian Federation of General Practitioners.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- ARB-Based Combination Therapy for the Clinical Management of Hypertension and Hypertension-Related Comorbidities: A Spotlight on Their Use in COVID-19 Patients.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Review
- Effects of Caloric Restriction Diet on Arterial Hypertension and Endothelial Dysfunction.Nutrients · 2021Review
- Blood Pressure Target Achievement Under Monotheraphy: A Real-Life Appraisal.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020Observational
- Clinical Use of Impedance Cardiography for Hemodynamic Assessment of Early Cardiovascular Disease and Management of Hypertension.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020Review
- Epidemiological Impact and Clinical Consequences of Masked Hypertension: A Narrative Review.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020Review
- Italian Society of Arterial Hypertension (SIIA) Position Paper on the Role of Renal Denervation in the Management of the Difficult-to-Treat Hypertensive Patient.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2020Review
Corrections and comments
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Authors and funding
19 authors at 16 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Observational clinical studies have demonstrated that only 30-40% of patients with arterial hypertension achieve the recommended blood pressure goals (below 140/90 mmHg). In contrast, interventional trials consistently showed that it is possible to achieve effective blood pressure targets in about 70% of treated hypertensive patients with different cardiovascular risk profiles, especially through the use of rational, effective and well tolerated combination therapies. In order to bridge the gap between current and desired blood pressure control and to achieve more effective prevention of cardiovascular diseases, the Italian Society of Hypertension (SIIA) has developed an interventional strategy aimed at reaching nearly 70% of treated controlled hypertensive patients by 2015. This ambitious goal can be realistically achieved by a more rational use of modern tools and supports, and also through the use of combination therapy in hypertension in daily clinical practice, especially if this approach can be simplified into a single pill (fixed combination therapy), which is a therapeutic option now also available in Italy. Since about 70-80% of treated hypertensive patients require a combination therapy based on at least two classes of drugs in order to achieve the recommended blood pressure goals, it is of key importance to implement this strategy in routine clinical practice. Amongst the various combination therapies currently available for hypertension treatment and control, the use of those strategies based on drugs that antagonize the renin-angiotensin system, such as angiotensin II type 1 receptor antagonists (angiotensin receptor blockers) and ACE inhibitors, in combination with diuretics and/or calcium channel blockers, has been shown to significantly reduce the risk of major cardiovascular events and to improve patient compliance to treatment, resulting in a greater antihypertensive efficacy and better tolerability compared with monotherapy. The present document of the Italian Society of Arterial Hypertension (SIIA) aims to gather the main indications for the implementation of combination therapy in the treatment of hypertension, in order to improve blood pressure control in Italy.
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