Evidence map›Paper›PMID 23536046›Full record

ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life2013

Potassium ions are more effective than sodium ions in salt induced peptide formation.

Michael V Dubina, Sergey Yu Vyazmin, Vitali M Boitsov, Eugene N Nikolaev, Igor A Popov, Alexey S Kononikhin, Igor E Eliseev, Yuri V Natochin

Open access · hybridAbstract read
In one paragraph

Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. The NaBiophysical reviews · 2023
    Review
  3. On the Role ofLife (Basel, Switzerland) · 2022
    Article
  4. Article
  5. Article
  6. Why Nature Chose Potassium.Journal of molecular evolution · 2019
    Review
  7. Article
  8. Interaction, at Ambient Temperature and 80 °C, between Minerals and Artificial Seawaters Resembling the Present Ocean Composition and that of 4.0 Billion Years Ago.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Michael V DubinaSt Petersburg Academic University - Nanotechnology Research and Education Centre RAS, 8/3 Khlopin str, 194021, St Petersburg, Russia. dubina@spbau.ru
Sergey Yu Vyazmin
Vitali M Boitsov
Eugene N Nikolaev
Igor A Popov
Alexey S Kononikhin
Igor E Eliseev
Yuri V Natochin
Saint Petersburg Academic University · RUInstitute of Energy Problems of Chemical Physics · RUInstitute of Evolutionary Physiology and Biochemistry · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prebiotic peptide formation under aqueous conditions in the presence of metal ions is one of the plausible triggers of the emergence of life. The salt-induced peptide formation reaction has been suggested as being prebiotically relevant and was examined for the formation of peptides in NaCl solutions. In previous work we have argued that the first protocell could have emerged in KCl solution. Using HPLC-MS/MS analysis, we found that K(+) is more than an order of magnitude more effective in the L-glutamic acid oligomerization with 1,1'-carbonyldiimidazole in aqueous solutions than the same concentration of Na(+), which is consistent with the diffusion theory calculations. We anticipate that prebiotic peptides could have formed with K(+) as the driving force, not Na(+), as commonly believed.

Indexed as

Cations, MonovalentChromatography, High Pressure LiquidGlutamic AcidImidazolesModels, TheoreticalPeptidesPotassiumSodiumSodium ChlorideTandem Mass SpectrometryCations, MonovalentGlutamic AcidImidazolesN,N-carbonyldiimidazolePeptidesPotassiumSodiumSodium Chloride

Identifiers

PMID23536046
PMCPMC3676736
OpenAlexW2094294216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.