ArticlePlant physiology2013
A genetic and metabolic analysis revealed that cotton fiber cell development was retarded by flavonoid naringenin.
Article in Plant physiology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed, 167 citations in OpenAlex.
- Integrated multi-omics analysis reveals distinct molecular features of key stages in cotton fiber development inFrontiers in plant science · 2026Article
- Genetic and biochemical analyses identify a major locus, GH-PA1, underlying pollen carotenoid accumulation and pigmentation in upland cotton.Journal of experimental botany · 2025Article
- Article
- GbSER02 Interacts With GhVOZ1 to Promote Fiber Elongation by Modulating Gibberellin Synthesis in Cotton.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Differential miRNA expression and regulatory mechanisms in pigmentation and fiber development of white and brown cotton (Gossypium hirsutum).Functional & integrative genomics · 2025Article
- Spatiotemporal transcriptome and metabolome landscapes of cotton fiber during initiation and early development.Nature communications · 2025Article
- Transcriptomic exploration yields novel perspectives on the regulatory network underlying trichome initiation inFrontiers in plant science · 2025Article
- TRANSPARENT TESTA 16 collaborates with the MYB-bHLH-WD40 transcriptional complex to produce brown fiber cotton.Plant physiology · 2024Article
- GhLCYε-3 characterized as a lycopene cyclase gene responding to drought stress in cotton.Computational and structural biotechnology journal · 2024Article
- Comparative Lipidomics Analysis Provides New Insights into the Metabolic Basis of Color Formation in Green Cotton Fiber.Plants (Basel, Switzerland) · 2024Article
- The WRKY46-MYC2 module plays a critical role in E-2-hexenal-induced anti-herbivore responses by promoting flavonoid accumulation.Plant communications · 2024Article
- Naturally colored cotton for wearable applications.Frontiers in plant science · 2024Review
- Morphological and transcriptomic responses/acclimations of erect-type submerged macrophyteEcology and evolution · 2023Article
- Article
- Cloning and functional analysis of GhDFR1, a key gene of flavonoid synthesis pathway in naturally colored cotton.Molecular biology reports · 2023Article
- Coordination of floral and fiber development in cotton (Gossypium) by hormone- and flavonoid-signalling associated regulatory miRNAs.Plant molecular biology · 2023Article
- GhWRKY41 forms a positive feedback regulation loop and increases cotton defence response against Verticillium dahliae by regulating phenylpropanoid metabolism.Plant biotechnology journal · 2023Article
- A glutathione S-transferase GhTT19 determines flower petal pigmentation via regulating anthocyanin accumulation in cotton.Plant biotechnology journal · 2023Article
- Comparative proteomic analysis identified proteins and the phenylpropanoid biosynthesis pathway involved in the response to ABA treatment in cotton fiber development.Scientific reports · 2023Article
- A reference-grade genome assembly for Gossypium bickii and insights into its genome evolution and formation of pigment glands and gossypol.Plant communications · 2023Article
13 more citing papers are in PubMed but not listed here.
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The cotton (Gossypium spp.) fiber is a unique elongated cell that is useful for investigating cell differentiation. Previous studies have demonstrated the importance of factors such as sugar metabolism, the cytoskeleton, and hormones, which are commonly known to be involved in plant cell development, while the secondary metabolites have been less regarded. By mining public data and comparing analyses of fiber from two cotton species (Gossypium hirsutum and Gossypium barbadense), we found that the flavonoid metabolism is active in early fiber cell development. Different flavonoids exhibited distinct effects on fiber development during ovule culture; among them, naringenin (NAR) could significantly retard fiber development. NAR is a substrate of flavanone 3-hydroxylase (F3H), and silencing the F3H gene significantly increased the NAR content of fiber cells. Fiber development was suppressed following F3H silencing, but the overexpression of F3H caused no obvious effects. Significant retardation of fiber growth was observed after the introduction of the F3H-RNA interference segment into the high-flavonoid brown fiber G. hirsutum T586 line by cross. A greater accumulation of NAR as well as much shorter fibers were also observed in the BC1 generation plants. These results suggest that NAR is negatively associated with fiber development and that the metabolism mediated by F3H is important in fiber development, thus highlighting that flavonoid metabolism represents a novel pathway with the potential for cotton fiber improvement.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.