ArticleParasitology research2013
Detection of Leishmania infantum and identification of blood meals in Phlebotomus perniciosus from a focus of human leishmaniasis in Madrid, Spain.
Article in Parasitology research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.
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Who cites it
57 citing papers in PubMed, 111 citations in OpenAlex.
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- Comparative quantification of Leishmania infantum in experimental phlebotomine sand fly infections using kDNA and single-copy Meta-1 gene qPCR assays.Parasites & vectors · 2026Article
- Characterization ofVeterinary sciences · 2025Article
- Molecular and Serological Detection ofAnimals : an open access journal from MDPI · 2025Article
- Agreement Document for the Study of Leishmaniasis from a One Health Approach in Spain.Tropical medicine and infectious disease · 2025Article
- Seroepidemiological Surveillance of Livestock Within an Endemic Focus of Leishmaniasis Caused byAnimals : an open access journal from MDPI · 2025Article
- Feline leishmaniosis in the Mediterranean Basin: a multicenter study.Parasites & vectors · 2024Article
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- Multihost/Multivector Community Network: Disentangling Sandfly Species and Host Interactions in Avian Habitats.Transboundary and emerging diseases · 2024Article
- One piece of the puzzle: Modeling vector presence and environment reveals seasonality, distribution, and prevalence of sandflies andOne health (Amsterdam, Netherlands) · 2023Article
- Blood Feeding Sources of Nyssomyia antunesi (Diptera: Psychodidae): A Suspected Vector of Leishmania (Kinetoplastida: Trypanosomatidae) in the Brazilian Amazon.Journal of medical entomology · 2022Article
- Exposure to Phlebotomus perniciosus sandfly vectors is positively associated with Toscana virus and Leishmania infantum infection in human blood donors in Murcia Region, southeast Spain.Transboundary and emerging diseases · 2022Article
- Clinical Case of Feline Leishmaniosis: Therapeutic Approach and Long-Term Follow-Up.Veterinary sciences · 2022Article
- Molecular detection of Leishmania infantum in rats and sand flies in the urban sewers of Barcelona, Spain.Parasites & vectors · 2022Article
- Investigation of Leishmania (Viannia) braziliensis Infection in Wild Mammals in Brazil.Acta parasitologica · 2022Article
- Phlebotomine sand flies (Diptera, Psychodidae) from Spain: an updated checklist and extended distributions.ZooKeys · 2022Article
- Wild Rabbit Exposure toMicroorganisms · 2021Article
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Since 2010, the number of cases of both human visceral leishmaniasis and cutaneous leishmaniasis in southwestern Madrid region (Spain) and more specifically in the town of Fuenlabrada has increased. Direct xenodiagnosis of leishmaniasis proved that hares (Lepus granatensis) from this focus are able to infect with Leishmania infantum colonized Phlebotomus perniciosus. To a better understanding of this focus of leishmaniasis, we conducted an entomological survey using CDC light traps, at the end of the seasonal transmission period of 2011 before the beginning of control measures of the disease, to study the phlebotomine sand flies species involved. Detection of Leishmania DNA in the sand flies captured was studied by kDNA-PCR and cpb-PCR. In addition, blood fed and gravid female P. perniciosus were analysed by a PCR based in vertebrate cytochrome b (cyt b) gene. Taxonomic identification of captured sand flies (n = 174) as P. perniciosus (n = 171) and Sergentomyia minuta (n = 3) together with the analysis of blood feeding in ten sand flies that shows a high preference for hares (n = 6), followed by humans (n = 3), and cats (n = 1) confirm a strong association between P. perniciosus hares and humans in the focus. Moreover, 79 out of 135 (58.5 %) P. perniciosus were positive to L. infantum by PCR approaches. These data support the increase of human leishmaniasis cases in the area and the existence of an unusual sylvatic cycle alternative to the classical domestic one, where the dog is the main reservoir of L. infantum.
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