Evidence map›Paper›PMID 23534825›Full record

ArticleThe Libyan journal of medicine2013

A combination of plasma DAO and citrulline levels as a potential marker for acute mesenteric ischemia.

Rıdvan Cakmaz, Oktay Büyükaşık, Nurettin Kahramansoy, Hayri Erkol, Cavit Cöl, Cetin Boran, Güler Buğdaycı

Open access · goldAbstract read
In one paragraph

Article in The Libyan journal of medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 38 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Rıdvan CakmazDepartment of General Surgery, State Hospital, Adıyaman, Turkey.
Oktay Büyükaşık
Nurettin Kahramansoy
Hayri Erkol
Cavit Cöl
Cetin Boran
Güler Buğdaycı
Bolu Abant İzzet Baysal University · TRAdıyaman University · TRLokman Hekim Üniversitesi · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThere is no valid and reliable diagnostic test for early diagnosis of acute mesenteric ischemia (AMI). The aim of this study was to measure the plasma levels of diamine oxidase (DAO) and citrulline in AMI to gain insight into its early diagnosis. MATERIAL AND

methodsA total of 21 Wistar albino rats were divided into three groups, that is, control group, short-term ischemia group, and prolonged ischemia group. The superior mesenteric artery was occluded for 15 min in the short-term ischemia group and for 12 h in the prolonged ischemia group. Twelve hours later, the experiment was terminated and plasma DAO and citrulline levels were measured. Intestinal tissue was evaluated for the histopathological changes.

resultsCompared to the control group, the short-term and prolonged ischemia groups showed significant increases in the plasma levels of DAO, whereas the plasma citrulline levels decreased significantly. Prolonged ischemia caused a larger increase in the plasma DAO levels and a larger decrease in the plasma citrulline levels compared to the short-term ischemia (p=0.011 and p=0.021, respectively). Intestinal damage was shown to develop more in the prolonged ischemia group (p=0.001).

conclusionIn the early period of AMI, the plasma DAO levels increase while citrulline levels decrease, and the extent of these changes depends on the duration of ischemia.

Indexed as

Amine Oxidase (Copper-Containing)AnimalsBiomarkersCase-Control StudiesCitrullineCreatinineEarly DiagnosisFemaleIntestinesIschemiaMesenteric Artery, SuperiorRatsRats, WistarTime FactorsUreaVascular DiseasesAmine Oxidase (Copper-Containing)BiomarkersCitrullineCreatinineUreaanimal modelcitrullinediamine oxidaseexperimentalintestines

Identifiers

PMID23534825
PMCPMC3609998
OpenAlexW2155129574

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.