ArticleStroke research and treatment2013
Depression after stroke and risk of mortality: a systematic review and meta-analysis.
Article in Stroke research and treatment, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
117 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Efficacy and safety of electroacupuncture for post-stroke depression: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Impact of depression on stroke outcomes among stroke survivors: Systematic review and meta-analysis.PloS one · 2023Pooled it
- Major Cardiac-Psychiatric Drug-Drug Interactions: a Systematic Review of the Consistency of Drug Databases.Cardiovascular drugs and therapy · 2021Pooled it
- Poststroke depression and risk of recurrent stroke: A meta-analysis of prospective studies.Medicine · 2019Pooled it
- Pooled it
- The association of depression and all-cause and cause-specific mortality: an umbrella review of systematic reviews and meta-analyses.BMC medicine · 2018Pooled it
- A meta-analysis of risk factors for depression in adults and children after natural disasters.BMC public health · 2014Pooled it
- The effect of intensive family-centered health education on the awareness rate, diagnosis, and treatment of post-stroke depression in community families.BMC primary care · 2022Trial
- The effects of a dialogue-based intervention to promote psychosocial well-being after stroke: a randomized controlled trial.Clinical rehabilitation · 2020Trial
- Trial
- Anxiety and Depressive Symptoms Among Two Seriously Medically Ill Populations and Their Family Caregivers: A Comparison and Clinical Implications.Neurocritical care · 2017Trial
- Trial
- Clinical Manifestation of Depression after Stroke: Is It Different from Depression in Other Patient Populations?PloS one · 2015Trial
- Association between depression and all-cause, cardiovascular, and non-cardiovascular mortality in the Spanish population: a prospective cohort study.Archives of public health = Archives belges de sante publique · 2026Article
- Article
- Prevalence, Predictors, and Prognosis of Depression After Transient Ischemic Attack: A Population-Based Study.Stroke · 2026Article
- Factors associated with antidepressant use following hospitalization for acute stroke.International journal of psychiatry in medicine · 2026Article
- Chronic stress, gut microbiota, and immunity: interconnections and implications for health.Molecular and cellular biochemistry · 2025Review
- "The stroke has already happened. You can't undo what has happened" emotions, coping, and adjustment in the experiences of southeast Asian people living with stroke - A qualitative study.Preventive medicine reports · 2025Article
- Article
57 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Depression after stroke may have great burden on the likelihood of functional recovery and long-term outcomes. Objective. To estimate the association between depression after stroke and subsequent mortality. Methods. A systematic search of articles using PubMed and Web of Science databases was performed. Odds ratios (ORs) and hazard ratios (HRs) were used as association measures for pooled analyses, based on random-effects models. Results. Thirteen studies, involving 59,598 subjects suffering from stroke (6,052 with and 53,546 without depression), had data suitable for meta-analysis. The pooled OR for mortality at followup in people suffering from depression after stroke was 1.22 (1.02-1.47). Subgroups analyses highlighted that only studies with medium-term followup (2-5 years) showed a statistically significant association between depression and risk of death. Four studies had data suitable for further analysis of pooled HR. The meta-analysis revealed a HR for mortality of 1.52 (1.02-2.26) among people with depression after stroke. Conclusions. Despite some limitations, this paper confirms the potential role of depression on post stroke mortality. The relationship between depression and mortality after stroke seems to be related to the followup duration. Further research is needed to clarify the nature of the association between depression after stroke and mortality.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.